大鼠LMAN1多肽(ab39824)
Key features and details
- Purity: > 70% HPLC
- Suitable for: Blocking, Neutralising
描述
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产品名称
大鼠LMAN1多肽 -
纯度
> 70 % HPLC. -
无动物成分
No -
性质
Synthetic -
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种属
Rat -
序列
FDSFDNDGKKNNPAI -
氨基酸
159 to 173
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相关产品
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Corresponding Antibody
技术指标
Our Abpromise guarantee covers the use of ab39824 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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应用
Blocking - Blocking peptide for Anti-LMAN1 antibody (ab32583)
Neutralising
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形式
Lyophilized -
Concentration information loading...
制备和贮存
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稳定性和存储
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycle.
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复溶Reconstitute with 0.1 ml of distilled water
常规信息
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别名
- Endoplasmic reticulum golgi intermediate compartment protein 53
- ER-Golgi intermediate compartment 53 kDa protein
- ERGIC-53
see all -
功能
Mannose-specific lectin. May recognize sugar residues of glycoproteins, glycolipids, or glycosylphosphatidyl inositol anchors and may be involved in the sorting or recycling of proteins, lipids, or both. The LMAN1-MCFD2 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. -
组织特异性
Ubiquitous. -
疾病相关
Defects in LMAN1 are THE cause of factor V and factor VIII combined deficiency type 1 (F5F8D1) [MIM:227300]; also known as multiple coagulation factor deficiency I (MCFD1). F5F8D1 is an autosomal recessive blood coagulation disorder characterized by bleeding symptoms similar to those in hemophilia or parahemophilia, that are caused by single deficiency of FV or FVIII, respectively. The most common symptoms are epistaxis, menorrhagia, and excessive bleeding during or after trauma. Plasma levels of coagulation factors V and VIII are in the range of 5 to 30% of normal. -
序列相似性
Contains 1 L-type lectin-like domain. -
翻译后修饰
The N-terminal may be partly blocked. -
细胞定位
Endoplasmic reticulum-Golgi intermediate compartment membrane. Golgi apparatus membrane. Endoplasmic reticulum membrane. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
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Datasheet download
文献 (0)
ab39824 尚未被引用在任何文献中。