概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Rat
    • 序列
      SLRRSSCFGGRIDRIGAQSGLGCNSFRY
    • 氨基酸
      1 to 28

相关产品

技术指标

Our Abpromise guarantee covers the use of ab42248 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-ANP antibody (ab14348)

  • 形式
    Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 0.1% Acetic acid

  • 复溶
    Store at 2-8°C lyophilised, resuspend in 0.1% acetic acid.

常规信息

  • 别名
    • ANF
    • ANF_HUMAN
    • ANP
    • ATFB6
    • Atrial natriuretic factor
    • Atrial natriuretic peptide
    • Atriopeptin
    • Cardiodilatin
    • Cardiodilatin-related peptide
    • Cardionatrin
    • CDD
    • CDD ANF
    • CDD-ANF
    • CDP
    • Natriuretic peptide A
    • Natriuretic peptide precursor A
    • NPPA
    • PND
    • Prepronatriodilatin
    see all
  • 功能
    Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • 疾病相关
    Atrial standstill 2
    Atrial fibrillation, familial, 6
  • 序列相似性
    Belongs to the natriuretic peptide family.
  • 翻译后修饰
    Cleaved by CORIN upon secretion to produce the functional hormone.
    Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.
  • 细胞定位
    Secreted.
  • Information by UniProt

文献

ab42248 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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