概述

  • 产品名称Anti-RASSF2抗体[EPR6621]
    参阅全部 RASSF2 一抗
  • 描述
    兔单克隆抗体[EPR6621] to RASSF2
  • 经测试应用适用于: WBmore details
    不适用于: Flow Cyt,ICC,IHC-P or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to residues at the C terminus of Human RASSF2.

  • 阳性对照
    • Raji, Jurkat and SH-SY5Y cell lysates.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

相关产品

应用

Our Abpromise guarantee covers the use of ab124786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000 - 1/10000. Predicted molecular weight: 37 kDa.
  • 应用说明Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
  • 靶标

    • 功能Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest.
    • 组织特异性Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.
    • 序列相似性Contains 1 Ras-associating domain.
      Contains 1 SARAH domain.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CENP 34 antibody
      • Centromere protein 34 antibody
      • Ras association (RalGDS/AF 6) domain family 2 antibody
      • Ras association (RalGDS/AF-6) domain family member 2 antibody
      • Ras association domain containing protein 2 antibody
      • Ras association domain-containing protein 2 antibody
      • RASF2_HUMAN antibody
      • RASFADIN antibody
      • RASSF2 antibody
      • RP4-599I11.1 antibody
      see all

    Anti-RASSF2 antibody [EPR6621] 图像

    • All lanes : Anti-RASSF2 antibody [EPR6621] (ab124786) at 1/1000 dilution

      Lane 1 : Raji cell lysate
      Lane 2 : Jurkat cell lysate
      Lane 3 : SH-SY5Y cell lysate

      Lysates/proteins at 10 µg per lane.

      Secondary
      Standard HRP labelled goat anti-rabbit at 1/2000 dilution

      Predicted band size : 37 kDa
    • Equilibrium disassociation constant (KD)
      Learn more about KD

      Click here to learn more about KD

    Anti-RASSF2 antibody [EPR6621] (ab124786)参考文献

    This product has been referenced in:
    • Guerrero-Setas D  et al. RASSF2 hypermethylation is present and related to shorter survival in squamous cervical cancer. Mod Pathol N/A:N/A (2013). IHC ; Human . Read more (PubMed: 23542458) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"