重组Anti-CDC25抗体[EPR1790(2)] (ab111830)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR1790(2)] to CDC25
- Suitable for: WB
- Reacts with: Human
Related conjugates and formulations
概述
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产品名称
Anti-CDC25抗体[EPR1790(2)]
参阅全部 CDC25 一抗 -
描述
兔单克隆抗体[EPR1790(2)] to CDC25 -
宿主
Rabbit -
特异性
This antibody detects the band of interest in tissue lysates, but it did not detect the protein in cell lysate.
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经测试应用
适用于: WBmore details
不适用于: Flow Cyt,ICC/IF,IHC-P or IP -
种属反应性
与反应: Human
预测可用于: Rat -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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阳性对照
- Human hippocampus, hypothalamus, and midbrain lysates.
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常规说明
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Mouse: We have preliminary internal testing data to indicate this antibody may not react with this species. Please contact us for more information.
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
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纯度
Protein A purified -
克隆
单克隆 -
克隆编号
EPR1790(2) -
同种型
IgG -
研究领域
相关产品
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Alternative Versions
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab111830于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/1000 - 1/10000. Predicted molecular weight: 145 kDa.
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说明 |
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WB
1/1000 - 1/10000. Predicted molecular weight: 145 kDa. |
靶标
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功能
Promotes the exchange of Ras-bound GDP by GTP. -
序列相似性
Contains 1 DH (DBL-homology) domain.
Contains 1 IQ domain.
Contains 1 N-terminal Ras-GEF domain.
Contains 2 PH domains.
Contains 1 Ras-GEF domain. -
结构域
The DH (DBL-homology) domain mediates interaction with RASGRF2. -
翻译后修饰
Ubiquitinated. - Information by UniProt
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数据库链接
- Entrez Gene: 5923 Human
- Entrez Gene: 192213 Rat
- Omim: 606600 Human
- SwissProt: Q13972 Human
- SwissProt: P28818 Rat
- Unigene: 459035 Human
- Unigene: 135776 Rat
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别名
- CDC25 antibody
- CDC25L antibody
- GNRP antibody
see all
图片
数据表及文件
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SDS download
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Datasheet download
文献 (2)
ab111830 被引用在 2 文献中.
- Jiang T et al. ALOX12B promotes carcinogenesis in cervical cancer by regulating the PI3K/ERK1 signaling pathway. Oncol Lett 20:1360-1368 (2020). PubMed: 32724378
- Watts JM et al. A Case of AML Characterized by a Novel t(4;15)(q31;q22) Translocation That Confers a Growth-Stimulatory Response to Retinoid-Based Therapy. Int J Mol Sci 18:N/A (2017). WB ; Human . PubMed: 28696354