概述

  • 产品名称
  • 描述
    山羊多克隆抗体to RASAL1
  • 经测试应用
    适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    C-QERGKAALGPLGP

    , corresponding to C terminal amino acids 792-804 of Human RASAL1

  • 阳性对照
    • Human Thyroid gland lysates.

性能

应用

Our Abpromise guarantee covers the use of ab58570 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明
    Peptide ELISA: limiting dilution: 1/32000.
    WB: Use at a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 90 kDa (predicted molecular weight: 90 kDa).
    An additional band of unknown identity was also consistently observed at 21kDa. This band was successfully blocked by incubation with the immunising peptide.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Probable inhibitory regulator of the Ras-cyclic AMP pathway.
    • 组织特异性
      Highly expressed in thyroid and adrenal medulla, lower expression in brain, spinal cord and trachea.
    • 序列相似性
      Contains 1 Btk-type zinc finger.
      Contains 2 C2 domains.
      Contains 1 PH domain.
      Contains 1 Ras-GAP domain.
    • Information by UniProt
    • 数据库链接
    • 形式
      It localizes to cytoplasm.
    • 别名
      • GAP1 like protein antibody
      • MRASAL antibody
      • RAS GTPase activating protein like antibody
      • RAS protein activator like 1 (GAP1 like) antibody
      • RAS protein activator like 1 antibody
      • RASAL antibody
      • Rasal1 antibody
      • rasGAP activating like protein 1 antibody
      • RasGAP-activating-like protein 1 antibody
      • RASGAP1 LIKE antibody
      • RASL1_HUMAN antibody
      see all

    图片

    • Anti-RASAL1 antibody (ab58570) at 0.3 µg/ml + Human Thyroid lysate at 35 µg

      Predicted band size : 90 kDa
      Observed band size : 90 kDa
      Additional bands at : 21 kDa. We are unsure as to the identity of these extra bands.

    实验方案

    文献

    ab58570 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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