概述

  • 产品名称
    Anti-RAP1GAP2抗体
  • 描述
    兔多克隆抗体to RAP1GAP2
  • 经测试应用
    适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 700-730 of Human RAP1GAP2

  • 阳性对照
    • HeLa cell lysate, Mouse brain tissue lysate, Human pancreas tissue

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at 4°C (up to 6 months). Store at -20°C long term.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    Purified through a protein A column, followed by peptide affinity purification.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab104176 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 80 kDa.
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能
    GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.
  • 组织特异性
    Isoform 1 and isoform 2 are expressed in platelets with isoform 2 being the predominant form. Expressed in lymphocytes, heart, testis and pancreas.
  • 序列相似性
    Contains 1 Rap-GAP domain.
  • 翻译后修饰
    In vitro phosphorylated by cGMP-dependent protein kinase 1 (cGKI) at Ser-7; the phosphorylation probably does not regulate GAP activity.
  • 细胞定位
    Cytoplasm. Cytoplasm, perinuclear region.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp686O238 antibody
    • GARNL4 antibody
    • GTPase activating RANGAP domain like 4 antibody
    • GTPase activating Rap/RanGAP domain like 4 antibody
    • GTPase activating Rap/RanGAP domain like protein 4 antibody
    • GTPase-activating Rap/Ran-GAP domain-like protein 4 antibody
    • KIAA1039 antibody
    • RAP1 GTPase activating protein 2 antibody
    • Rap1 GTPase-activating protein 2 antibody
    • RAP1GA3 antibody
    • Rap1GAP2 antibody
    • RPGP2_HUMAN antibody
    see all

Anti-RAP1GAP2 antibody 图像

  • Anti-RAP1GAP2 antibody (ab104176) at 1/100 dilution + HeLa cell lysate at 35 µg

    Predicted band size : 80 kDa
  • Anti-RAP1GAP2 antibody (ab104176) at 1/100 dilution + Mouse brain tissue lysate at 35 µg/ml

    Predicted band size : 80 kDa
  • ab104176, at 1/50 dilution, staining RAP1GAP2 in formalin fixed and paraffin embedded Human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Anti-RAP1GAP2 antibody (ab104176)参考文献

ab104176 has not yet been referenced specifically in any publications.

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