重组
RabMAb

Anti-RANTES抗体[EPR1359] (ab108933)

概述

  • 产品名称
    Anti-RANTES抗体[EPR1359]
    参阅全部 RANTES 一抗
  • 描述
    兔单克隆抗体[EPR1359] to RANTES
  • 经测试应用
    适用于: WB, ICCmore details
    不适用于: Flow Cyt,IHC-P or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to a region within Human RANTES.

  • 阳性对照
    • RANTES recombinant protein
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

    Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents

性能

应用

Our Abpromise guarantee covers the use of ab108933 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/50000. Predicted molecular weight: 10 kDa.
ICC 1/100 - 1/250.
  • 应用说明
    Is unsuitable for Flow Cyt,IHC-P or IP.
  • 靶标

    • 功能
      Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils.
    • 组织特异性
      T-cell and macrophage specific.
    • 序列相似性
      Belongs to the intercrine beta (chemokine CC) family.
    • 翻译后修饰
      N-terminal processed form RANTES(3-68) is produced by proteolytic cleavage, probably by DPP4, after secretion from peripheral blood leukocytes and cultured sarcoma cells.
      The identity of the O-linked saccharides at Ser-27 and Ser-28 are not reported in PubMed:1380064. They are assigned by similarity.
    • 细胞定位
      Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Beta chemokine RANTES antibody
      • Beta chemokine RANTES precursor antibody
      • C C motif chemokine 5 antibody
      • CCL 5 antibody
      • CCL5 antibody
      • CCL5_HUMAN antibody
      • Chemokine (C C motif) ligand 5 antibody
      • Chemokine CC Motif Ligand 5 antibody
      • D17S136E antibody
      • EoCP antibody
      • Eosinophil chemotactic cytokine antibody
      • MGC17164 antibody
      • RANTES(4-68) antibody
      • Regulated upon activation normally T expressed and presumably secreted antibody
      • SCYA 5 antibody
      • SCYA5 antibody
      • SIS delta antibody
      • SIS-delta antibody
      • SISd antibody
      • Small inducible cytokine A5 (RANTES) antibody
      • Small inducible cytokine A5 antibody
      • Small inducible cytokine subfamily A (Cys Cys) member 5 antibody
      • Small-inducible cytokine A5 antibody
      • T cell specific protein p288 antibody
      • T cell specific RANTES protein antibody
      • T cell-specific protein P228 antibody
      • T-cell-specific protein RANTES antibody
      • TCP 228 antibody
      • TCP228 antibody
      see all

    图片

    • Anti-RANTES antibody [EPR1359] (ab108933) at 1/50000 dilution + RANTES recombinant protein at 0.01 µg

      Predicted band size : 10 kDa

    文献

    ab108933 has not yet been referenced specifically in any publications.

    客户评价及客户问答

    Thank you for contacting us.

    The protein sequence compatibility between human and mouse with bovine is about 80% which is very close for antibody cross reactivity. We unfortunately haven't tested any of the antibody with bovine CCL5 so I am so...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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