概述

  • 产品名称Anti-Ran抗体
    参阅全部 Ran 一抗
  • 描述
    兔多克隆抗体to Ran
  • 特异性Observed cross-reactivity with ~26 kDa tag.
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Saccharomyces cerevisiae
  • 免疫原

    Recombinant fusion protein (S. cerevisiae).

性能

应用

Our Abpromise guarantee covers the use of ab11693 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 26 kDa).
ICC/IF Use at an assay dependent dilution.

靶标

  • 功能GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). The complex with BIRC5/ survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules.
    Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.
  • 组织特异性Expressed in a variety of tissues.
  • 序列相似性Belongs to the small GTPase superfamily. Ran family.
  • 翻译后修饰The N-terminus is blocked.
  • 细胞定位Nucleus. Cytoplasm. Melanosome. Becomes dispersed throughout the cytoplasm during mitosis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt
  • 别名
    • Androgen receptor associated protein 24 antibody
    • Androgen receptor-associated protein 24 antibody
    • ARA 24 antibody
    • ARA24 antibody
    • Gsp1 antibody
    • GTP binding nuclear protein RAN antibody
    • GTP-binding nuclear protein Ran antibody
    • GTPase Ran antibody
    • Guanosine triphosphatase Ran antibody
    • LPS antibody
    • OK/SW-cl.81 antibody
    • ran antibody
    • RAN member RAS oncogene family antibody
    • RAN_HUMAN antibody
    • RanGTPase antibody
    • Ras like protein TC4 antibody
    • Ras related nuclear protein antibody
    • Ras-like protein TC4 antibody
    • Ras-related nuclear protein antibody
    • RASL2 8 antibody
    • TC 4 antibody
    • TC4 antibody
    see all

Anti-Ran antibody 图像



  • Predicted band size : 26 kDa


    ab11693 at a 1/1000 dilution staining approximately 25kDa Ran in S.cerevisiae whole cell lysate by Western blot (ECL).

Anti-Ran antibody (ab11693)参考文献

This product has been referenced in:
  • Muniyappa MK  et al. MiRNA-29a regulates the expression of numerous proteins and reduces the invasiveness and proliferation of human carcinoma cell lines. Eur J Cancer 45:3104-18 (2009). WB ; Human . Read more (PubMed: 19818597) »

See 1 Publication for this product

Product Wall

Thank you for contacting us. Unfortunately, other than ab11693 which cross-reacts with the 26 kDa tag, our other Ran antibodies are raised against human Ran. Most would be unlikely to cross-react with yeast, due to low sequence homology with their immu...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"