概述

  • 产品名称Anti-RAIDD抗体[EPR1640Y]
    参阅全部 RAIDD 一抗
  • 描述
    兔单克隆抗体[EPR1640Y] to RAIDD
  • 经测试应用适用于: WB, IP, ICC, Flow Cyt, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to residues from the C terminus of human RAIDD.

  • 阳性对照
    • HeLa cell lysate and Human heart muscle tissue.
  • 常规说明

    This product is a recombinant rabbit monoclonal antibody.

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

应用

Our Abpromise guarantee covers the use of ab52621 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Detects a band of approximately 23 kDa (predicted molecular weight: 23 kDa).
IP 1/30.
ICC 1/100 - 1/250.
Flow Cyt 1/20.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

靶标

  • 功能Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
  • 组织特异性Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
  • 序列相似性Contains 1 CARD domain.
    Contains 1 death domain.
  • 结构域Contains a death domain involved in the binding of RIP protein.
    The CARD domain mediates the interaction with caspase-2.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CASP2 and RIPK1 domain containing adaptor with death domain antibody
    • Caspase and RIP adapter with death domain antibody
    • Caspase and RIP adaptor with death domain antibody
    • Cradd antibody
    • CRADD_HUMAN antibody
    • Death adaptor molecule RAIDD antibody
    • Death domain containing protein CRADD antibody
    • Death domain-containing protein CRADD antibody
    • MGC9163 antibody
    • RIP associated ICH1/CED3 homologous protein with death domain antibody
    • RIP associated protein with a death domain antibody
    • RIP-associated protein with a death domain antibody
    see all

Anti-RAIDD antibody [EPR1640Y] 图像

  • Anti-RAIDD antibody [EPR1640Y] (ab52621) at 1/1000 dilution + HeLa cell lysate at 10 µg

    Secondary
    goat anti-rabbit HRP at 1/2000 dilution

    Predicted band size : 23 kDa
    Observed band size : 23 kDa
  • ab52621, at a 1/50 dilution, staining Human RAIDD in heart muscle, using Immunohistochemistry, Paraffin embedded tissue.

Anti-RAIDD antibody [EPR1640Y] (ab52621)参考文献

This product has been referenced in:

See 1 Publication for this product

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