兔单克隆抗体[EPR1639] to RAIDD
A synthetic peptide corresponding to residues in human RAIDD
Raji, HeLa, K562 and MCF7 cell lysates.
This product is a recombinant rabbit monoclonal antibody.
Mouse: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.
® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab ® patents
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Tissue culture supernatant
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/1000 - 1/5000. Predicted molecular weight: 23 kDa.
1/100 - 1/250.
ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
Is unsuitable for IHC-P.
Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
Contains 1 CARD domain.
Contains 1 death domain.
Contains a death domain involved in the binding of RIP protein.
The CARD domain mediates the interaction with caspase-2.
Information by UniProt
CASP2 and RIPK1 domain containing adaptor with death domain antibody
Caspase and RIP adapter with death domain antibody
Caspase and RIP adaptor with death domain antibody
Anti-RAIDD antibody [EPR1639] 图像
Anti-RAIDD antibody [EPR1639] (ab76465)参考文献
This product has been referenced in:
Di Donato N
et al. Mutations in CRADD Result in Reduced Caspase-2-Mediated Neuronal Apoptosis and Cause Megalencephaly with a Rare Lissencephaly Variant. Am J Hum Genet 99:1117-1129 (2016).
Read more (PubMed: 27773430) »
See 1 Publication
for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"