概述

  • 产品名称Anti-RAIDD抗体
    参阅全部 RAIDD 一抗
  • 描述
    兔多克隆抗体to RAIDD
  • 特异性ab110914 detects an ~24 kD protein, corresponding to the apparent molecular mass of RAIDD on SDS-PAGE immunoblots. This 24 kD band, as well as a 67 kD band, can be specifically inhibited by the relevant peptide.
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Hamster, Monkey
  • 免疫原

    Synthetic peptide, corresponding to a region within Human RAIDD.

  • 阳性对照
    • Formalin fixed, paraffin embedded Human skeletal muscle. Formalin fixed, paraffin embedded Human placenta. Formalin fixed, paraffin embedded Human testis.

性能

应用

Our Abpromise guarantee covers the use of ab110914 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500. Predicted molecular weight: 23 kDa.
IHC-P Use a concentration of 10 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.
  • 组织特异性Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.
  • 序列相似性Contains 1 CARD domain.
    Contains 1 death domain.
  • 结构域Contains a death domain involved in the binding of RIP protein.
    The CARD domain mediates the interaction with caspase-2.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CASP2 and RIPK1 domain containing adaptor with death domain antibody
    • Caspase and RIP adapter with death domain antibody
    • Caspase and RIP adaptor with death domain antibody
    • Cradd antibody
    • CRADD_HUMAN antibody
    • Death adaptor molecule RAIDD antibody
    • Death domain containing protein CRADD antibody
    • Death domain-containing protein CRADD antibody
    • MGC9163 antibody
    • RIP associated ICH1/CED3 homologous protein with death domain antibody
    • RIP associated protein with a death domain antibody
    • RIP-associated protein with a death domain antibody
    see all

Anti-RAIDD antibody 图像

  • ab110914, at 10 µg/ml, staining RAIDD in formalin fixed, paraffin embedded Human skeletal muscle tissue by Immunohistochemistry. Biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen was used to develop the staining.
  • ab110914, at 10 µg/ml, staining RAIDD in formalin fixed, paraffin embedded Human placenta tissue by Immunohistochemistry. Biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen was used to develop the staining.
  • ab110914, at 10 µg/ml, staining RAIDD in formalin fixed, paraffin embedded Human testis by Immunohistochemistry. Biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen was used to develop the staining.

Anti-RAIDD antibody (ab110914)参考文献

ab110914 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab110914.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"