Anti-RAI3抗体- C-terminal (ab71121)

概述

  • 产品名称
    Anti-RAI3抗体- C-terminal
    参阅全部 RAI3 一抗
  • 描述
    兔多克隆抗体to RAI3 - C-terminal
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide from the C-terminal region of human RAI3 conjugated to KLH

  • 阳性对照
    • A375 cell lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    ab71121 is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab71121 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/1000.
WB 1/100 - 1/500. Detects a band of approximately 40 kDa (predicted molecular weight: 40 kDa).

靶标

  • 功能
    Unknown. This G-protein coupled receptor could be involved in modulating differentiation and maintaining homeostasis of epithelial cells. The comparable expression level in fetal lung and kidney with adult tissues suggests a possible role in embryonic development and maturation of these organs. This retinoic acid-inducible GPCR provide evidence for a possible interaction between retinoid and G-protein signaling pathways.
  • 组织特异性
    Expressed at high level in fetal and adult lung tissues. Constitutively expressed in fetal kidney and adult placenta, kidney, prostate, testis, ovary, small intestine, colon, stomach, and spinal chord at low to moderate levels. Not detectable in fetal heart, brain, and liver and adult heart, brain, liver, skeletal muscle, pancreas, spleen, thymus, and peripheral leukocytes. According to PubMed:10783259, expressed at low but detectable level in pancreas and heart.
  • 序列相似性
    Belongs to the G-protein coupled receptor 3 family.
  • 细胞定位
    Cell membrane. Cytoplasmic vesicle membrane. Localized in the plasma membrane and perinuclear vesicles.
  • Information by UniProt
  • 数据库链接
  • 别名
    • G protein coupled receptor family C group 5 member A antibody
    • G-protein coupled receptor family C group 5 member A antibody
    • GPCR 5A antibody
    • GPCR5A antibody
    • Gprc 5a antibody
    • Gprc5a antibody
    • Orphan G protein coupling receptor PEIG 1 antibody
    • Orphan G protein coupling receptor PEIG1 antibody
    • Orphan G-protein-coupling receptor PEIG-1 antibody
    • RAI 3 antibody
    • RAI3_HUMAN antibody
    • Raig 1 antibody
    • RAIG-1 antibody
    • Raig1 antibody
    • Retinoic acid induced 3 antibody
    • Retinoic acid induced gene 1 protein antibody
    • Retinoic acid induced protein 3 antibody
    • Retinoic acid responsive antibody
    • Retinoic acid responsive gene antibody
    • Retinoic acid-induced gene 1 protein antibody
    • Retinoic acid-induced protein 3 antibody
    see all

图片

  • Anti-RAI3 antibody - C-terminal (ab71121) at 1/100 dilution + A375 lysate at 12.5 µg

    Predicted band size : 40 kDa
    Observed band size : 40 kDa
    Additional bands at : 25 kDa,50 kDa. We are unsure as to the identity of these extra bands.
  • Anti-RAI3 antibody - C-terminal (ab71121) at 1/100 dilution + T47D lysate at 12.5 µg

    Predicted band size : 40 kDa
    Observed band size : 40 kDa

实验方案

文献

ab71121 has not yet been referenced specifically in any publications.

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