Anti-Rad6抗体[2782C5] (ab50889)
Key features and details
- Mouse monoclonal [2782C5] to Rad6
- Suitable for: IHC-M, WB
- Isotype: IgG2a
概述
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产品名称
Anti-Rad6抗体[2782C5]
参阅全部 Rad6 一抗 -
描述
小鼠单克隆抗体[2782C5] to Rad6 -
宿主
Mouse -
经测试应用
适用于: IHC-M, WBmore details -
免疫原
Recombinant fragment corresponding to Human Rad6 (internal sequence).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
pH: 7.40
Preservative: 0.05% Sodium azide
Constituents: 1% BSA, PBS -
Concentration information loading...
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纯度
Protein G purified -
克隆
单克隆 -
克隆编号
2782C5 -
同种型
IgG2a -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab50889于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IHC-M |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 17 kDa.
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说明 |
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IHC-M
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. Predicted molecular weight: 17 kDa. |
靶标
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功能
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA. -
通路
Protein modification; protein ubiquitination. -
序列相似性
Belongs to the ubiquitin-conjugating enzyme family. - Information by UniProt
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别名
- BHR6A antibody
- hHR6A antibody
- HR6A antibody
see all
图片
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Anti-Rad6 antibody [2782C5] (ab50889) + immunizing peptide
Predicted band size: 17 kDa
Observed band size: 34 kDa why is the actual band size different from the predicted?
数据表及文件
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Datasheet download
文献 (0)
ab50889 尚未被引用在任何文献中。