概述

  • 产品名称Anti-RAD52抗体
    参阅全部 RAD52 一抗
  • 描述
    兔多克隆抗体to RAD52
  • 经测试应用适用于: WB, IP, Electron Microscopy, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human).

性能

应用

Our Abpromise guarantee covers the use of ab18264 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 46 kDa.
IP Use at an assay dependent dilution.
Electron Microscopy Use at an assay dependent dilution.
ICC/IF 1/100 - 1/200.

靶标

  • 功能Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase.
  • 序列相似性Belongs to the RAD52 family.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DNA repair protein RAD52 antibody
    • DNA repair protein RAD52 antibody
    • DNA repair protein RAD52 homolog antibody
    • RAD 52 antibody
    • Rad52 antibody
    • RAD52 homolog (S. cerevisiae) antibody
    • RAD52 homolog (S. cerevisiae) antibody
    • RAD52 homolog antibody
    • RAD52_HUMAN antibody
    • Recombination protein RAD52 antibody
    • Recombination protein RAD52 antibody
    • Rhabdomyosarcoma antigen MU RMS 40.23 antibody
    see all

Anti-RAD52 antibody (ab18264)参考文献

This product has been referenced in:
  • Ahn JW  et al. SERBP1 affects homologous recombination-mediated DNA repair by regulation of CtIP translation during S phase. Nucleic Acids Res 43:6321-33 (2015). Read more (PubMed: 26068472) »
  • Tang KW  et al. Rad51 and Rad52 are involved in homologous recombination of replicating herpes simplex virus DNA. PLoS One 9:e111584 (2014). Human . Read more (PubMed: 25365323) »

See all 3 Publications for this product

Product Wall

Thank you for your patience. The originator has informed me that they do not have the immunogen sequence for ab18264 but can say that the immunogen was a His tagged pure full length recombinant Rad52. I am sorry I can't be of more assistance in ...

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Abcam guarantees this product to work in the species/application used in this Abreview.
Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (HeLa)
Specification HeLa
Fixative Paraformaldehyde
Username

Dr. Kirk McManus

Verified customer

提交于 Oct 03 2006

Thank you for your patience waiting for a response to your enquiry. I have now received details of a reference for this antibody (ab18264): The Embo Journal. 18 (22), p6552-6560 1999. The meiosis specific recombinase hDmcl forms ring structures a...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"