Anti-Rad51L1抗体[RAD51B 1E11/6] (ab11050)

概述

  • 产品名称Anti-Rad51L1抗体[RAD51B 1E11/6]
    参阅全部 Rad51L1 一抗
  • 描述
    小鼠单克隆抗体[RAD51B 1E11/6] to Rad51L1
  • 特异性Recognises as little as 10 ng of purified protein. Does not cross-react with Rad51C, Rad51D, Rad51, XRCC2 or XRCC3 in westerns.
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Hamster, Human
  • 免疫原

    His-tagged human Rad51L1

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: PBS
  • Concentration information loading...
  • 纯度Protein A purified
  • 纯化说明Purified on a talon affinity column under denaturing conditions, followed by gel purification on a SDS-PAGE.
  • 克隆单克隆
  • 克隆编号RAD51B 1E11/6
  • 骨髓瘤Sp2/0-Ag14
  • 同种型unknown
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab11050 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use at an assay dependent dilution. Predicted molecular weight: 42 kDa.

靶标

  • 功能Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. May promote the assembly of presynaptic RAD51 nucleoprotein filaments. The RAD51B-RAD51C dimer exhibits single-stranded DNA-dependent ATPase activity. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA.
  • 组织特异性Expressed in a wide range of tissues.
  • 疾病相关Note=A chromosomal aberration involving RAD51L1 is found in pulmonary chondroid hamartoma. Translocation t(6;14)(p21;q23-24) with HMGA1.
    Note=A chromosomal aberration involving RAD51L1 is found in uterine leiomyoma. Translocation t(12;14)(q15;q23-24) with HMGA2.
  • 序列相似性Belongs to the RecA family. RAD51 subfamily.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DNA repair protein RAD51 homolog 2 antibody
    • hREC2 antibody
    • MGC34245 antibody
    • OTTHUMP00000212251 antibody
    • OTTHUMP00000212253 antibody
    • OTTHUMP00000212254 antibody
    • OTTHUMP00000212255 antibody
    • R51H2 antibody
    • RA51B_HUMAN antibody
    • RAD51 homolog B (S. cerevisiae) antibody
    • RAD51 homolog B antibody
    • RAD51 like 1 antibody
    • RAD51 like protein 1 antibody
    • RAD51-like protein 1 antibody
    • Rad51B antibody
    • RAD51L1 antibody
    • REC2 antibody
    • RecA like protein antibody
    • Recombination repair protein antibody
    see all

Anti-Rad51L1 antibody [RAD51B 1E11/6] (ab11050)参考文献

This product has been referenced in:

See 1 Publication for this product

Product Wall

Thank you for your enquiry and for your patience. Ab11050 recognizes a weak band at the right size on whole cell extracts, but also a lot of non-specific bands. Better results were observed using purified protein. If you have any more questions, please...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"