概述

  • 产品名称Anti-RAC2抗体(HRP)
    参阅全部 RAC2 一抗
  • 描述
    山羊多克隆抗体to RAC2 (HRP)
  • 偶联物HRP
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide:

    PQPTRQQKRACSLL

    , corresponding to C terminal amino acids 179-192 of Human RAC2 according to NP_002863.1.

  • 阳性对照
    • MOLT4 lysates.
  • 常规说明

    Conjugated via amine groups to horseradish peroxidise.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C.
  • 存储溶液Preservative: 0.1% Proclin
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab124168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/1000. Predicted molecular weight: 21 kDa.

靶标

  • 功能Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. Augments the production of reactive oxygen species (ROS) by NADPH oxidase.
  • 组织特异性Hematopoietic specific.
  • 疾病相关Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome (NEUID) [MIM:608203].
  • 序列相似性Belongs to the small GTPase superfamily. Rho family.
  • 细胞定位Cytoplasm. Membrane-associated when activated.
  • Information by UniProt
  • 数据库链接
  • 形式Rac2 has high sequence homology with other Rac proteins. Therefore some antibodies may show cross-reactivity.
  • 别名
    • EN 7 antibody
    • EN-7 antibody
    • EN7 antibody
    • GX antibody
    • HSPC 022 antibody
    • HSPC022 antibody
    • p21 Rac 2 antibody
    • p21 Rac2 antibody
    • p21-Rac2 antibody
    • p21Rac2 antibody
    • RAC 2 antibody
    • Rac2 antibody
    • RAC2_HUMAN antibody
    • Ras related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2 antibody
    • Ras related C3 botulinum toxin substrate 2 antibody
    • Ras related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac2) antibody
    • Ras related C3 botulinum toxin substrate 3 antibody
    • Ras-related C3 botulinum toxin substrate 2 antibody
    • Rho family small GTP binding protein Rac 2 antibody
    • Rho family small GTP binding protein Rac2 antibody
    • Small G protein antibody
    see all

Anti-RAC2 antibody (HRP) 图像

  • Anti-RAC2 antibody (HRP) (ab124168) at 1/1000 dilution + MOLT4 cell lysates at 35 µg
    Developed using the ECL technique

    Predicted band size : 21 kDa

Anti-RAC2 antibody (HRP) (ab124168)参考文献

ab124168 has not yet been referenced specifically in any publications.

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