概述

  • 产品名称Anti-Rab11A抗体
    参阅全部 Rab11A 一抗
  • 描述
    山羊多克隆抗体to Rab11A
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Human
  • 免疫原

    Synthetic peptide:

    TENKPKVQCCQNI

    , corresponding to C terminal amino acids 204-216 of Human Rab11A.

  • 阳性对照
    • Mouse Heart lysate
  • 常规说明Principal Names – RAB11A; YL8; RAB11A, member RAS oncogene family; RAB 11A, member oncogene family Official Gene Symbol - RAB11A GenBank Accession Number – NP_004654 LocusLink ID - 55072 (human) Gene Ontology terms - RAB small monomeric GTPase

性能

应用

Our Abpromise guarantee covers the use of ab2921 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明Western Blot – Approx 25-28kDa band seen in Mouse Heart lysate (predicted MW 25kDa). Recommended for use at 1.0-3.0ug/ml.
  • 靶标

    • 功能Regulates endocytic recycling. May exert its functions by interacting with multiple effector proteins in different complexes. Acts as a major regulator of membrane delivery during cytokinesis. Together with MYO5B and RAB8A participates in epithelial cell polarization. Together with RAB3IP, RAB8A, the exocyst complex, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity). Together with MYO5B participates in CFTR trafficking to the plasma membrane and TF (Transferrin) recycling in nonpolarized cells. Required in a complex with MYO5B and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Participates in the sorting and basolateral transport of CDH1 from the Golgi apparatus to the plasma membrane. Regulates the recycling of FCGRT (receptor of Fc region of monomeric Ig G) to basolateral membranes.
    • 序列相似性Belongs to the small GTPase superfamily. Rab family.
    • 细胞定位Cell membrane. Recycling endosome membrane. Cleavage furrow. Translocates with RAB11FIP2 from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane. Localizes to the cleavage furrow. Colocalizes with PARD3, PRKCI, EXOC5, OCLN, PODXL and RAB8A in apical membrane initiation sites (AMIS) during the generation of apical surface and luminogenesis.
    • Information by UniProt
    • 数据库链接
    • 别名
      • MGC1490 antibody
      • Rab 11 antibody
      • Rab 11A antibody
      • RAB 11A, member oncogene family antibody
      • Rab-11 antibody
      • RAB11 A antibody
      • RAB11 antibody
      • Rab11a antibody
      • RAB11A member RAS oncogene family antibody
      • Ras related protein Rab 11A antibody
      • Ras related protein Rab11A antibody
      • Ras-related protein Rab-11A antibody
      • RB11A_HUMAN antibody
      • YL 8 antibody
      • YL8 antibody
      see all

    Anti-Rab11A antibody (ab2921)参考文献

    ab2921 has not yet been referenced specifically in any publications.

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