Anti-RAB11-FIP2抗体(ab104723)

概述

  • 产品名称Anti-RAB11-FIP2抗体
    参阅全部 RAB11-FIP2 一抗
  • 描述
    兔多克隆抗体to RAB11-FIP2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 71-120 (LLIQGSPEKY ILFLIVMHRS LVGLDKFLGQ VAINLNDIFE DKQRRKTEWF) of Human RAB11-FIP2 (NP_055719).

  • 阳性对照
    • COLO205 cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab104723 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.
  • 序列相似性Contains 1 C2 domain.
    Contains 1 FIP-RBD domain.
  • 翻译后修饰Phosphorylation at Ser-227 by MARK2 regulates epithelial cell polarity.
  • 细胞定位Cell membrane. Recycling endosome membrane. Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KIAA0941 antibody
    • NRip11 antibody
    • RAB11 family interacting protein 2 (class I) antibody
    • Rab11 family-interacting protein 2 antibody
    • RAB11 FIP2 long isoform antibody
    • Rab11-FIP2 antibody
    • RAB11FIP2 antibody
    • RFIP2 antibody
    • RFIP2_HUMAN antibody
    see all

Anti-RAB11-FIP2 antibody 图像

  • Anti-RAB11-FIP2 antibody (ab104723) at 1 µg/ml + COLO205 cell lysate at 10 µg

    Predicted band size : 58 kDa

Anti-RAB11-FIP2 antibody (ab104723)参考文献

ab104723 has not yet been referenced specifically in any publications.

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