Nguyen QL et al.Platelets from pulmonary hypertension patients show increased mitochondrial reserve capacity.JCI Insight 2:e91415 (2017).
Subramani K et al.Mitochondrial targeting by dichloroacetate improves outcome following hemorrhagic shock.Sci Rep 7:2671 (2017).
Lilla N et al.First Description of Reduced Pyruvate Dehydrogenase Enzyme Activity Following Subarachnoid Hemorrhage (SAH).Front Neurosci 11:37 (2017).
Zhang Y et al.Induction of Posttranslational Modifications of Mitochondrial Proteins by ATP Contributes to Negative Regulation of Mitochondrial Function.PLoS One 11:e0150454 (2016).
Golias T et al.Hypoxic repression of pyruvate dehydrogenase activity is necessary for metabolic reprogramming and growth of model tumours.Sci Rep 6:31146 (2016).
Sun J et al.Induction of triglyceride accumulation and mitochondrial maintenance in muscle cells by lactate.Sci Rep 6:33732 (2016).
Shanmughapriya S et al.Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.Sci Signal 8:ra23 (2015).
Prabhu A et al.Cysteine catabolism: a novel metabolic pathway contributing to glioblastoma growth.Cancer Res 74:787-96 (2014).
Yamane K et al.Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza.PLoS One 9:e98032 (2014).
Sheriff S et al.Des-acyl-ghrelin (DAG) normalizes hyperlactacidemia and improves survival in a lethal rat model of burn trauma.Peptides 60:1-7 (2014).
Hamabe A et al.Combined evaluation of hexokinase 2 and phosphorylated pyruvate dehydrogenase-E1a in invasive front lesions of colorectal tumors predicts cancer metabolism and patient prognosis.Cancer Sci 105:1100-8 (2014).
van der Veen JN et al.The concentration of phosphatidylethanolamine in mitochondria can modulate ATP production and glucose metabolism in mice.Diabetes 63:2620-30 (2014).
Kageyama Y et al.Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain.EMBO J 33:2798-813 (2014).
Morten KJ et al.Differential regulation of HIF-mediated pathways increases mitochondrial metabolism and ATP production in hypoxic osteoclasts.J Pathol 229:755-64 (2013).
Phillips BE et al.Effect of colon cancer and surgical resection on skeletal muscle mitochondrial enzyme activity in colon cancer patients: a pilot study.J Cachexia Sarcopenia Muscle 4:71-7 (2013).
Geng X et al.Synergetic neuroprotection of normobaric oxygenation and ethanol in ischemic stroke through improved oxidative mechanism.Stroke 44:1418-25 (2013).
Gu F et al.Alterations in mitochondrial DNA copy number and the activities of electron transport chain complexes and pyruvate dehydrogenase in the frontal cortex from subjects with autism.Transl Psychiatry 3:e299 (2013).
Jing E et al.Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation.Diabetes 62:3404-17 (2013).
Ota A et al.Effects of aripiprazole and clozapine on the treatment of glycolytic carbon in PC12 cells.J Neural Transm : (2012).
Thomas SN et al.Quantitative proteomic analysis of mitochondrial proteins reveals prosurvival mechanisms in the perpetuation of radiation-induced genomic instability.Free Radic Biol Med 53:618-28 (2012).
Hong JK et al.Growth factor withdrawal in combination with sodium butyrate addition extends culture longevity and enhances antibody production in CHO cells.J Biotechnol 155:225-31 (2011).
Yi X et al.Genetic reduction of lipoic acid synthase expression modestly increases atherosclerosis in male, but not in female, apolipoprotein E-deficient mice.Atherosclerosis 211:424-30 (2010).
Puthanveetil P et al.The increase in cardiac pyruvate dehydrogenase kinase-4 after short-term dexamethasone is controlled by an Akt-p38-forkhead box other factor-1 signaling axis.Endocrinology 151:2306-18 (2010).
Lee DW et al.Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease.J Biol Chem 284:29065-76 (2009).
Sikder D & Kodadek T The neurohormone orexin stimulates hypoxia-inducible factor-1 activity.Genes Dev 21:2995-3005 (2007).