概述

  • 产品名称Anti-PYGM抗体
    参阅全部 PYGM 一抗
  • 描述
    兔多克隆抗体to PYGM
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to Human PYGM aa 800-842 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • 阳性对照
    • Skeletal muscle

性能

应用

Our Abpromise guarantee covers the use of ab60982 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 20 µg/ml.

靶标

  • 功能Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  • 疾病相关Defects in PYGM are the cause of glycogen storage disease type 5 (GSD5) [MIM:232600]; also known as McArdle disease. GSD5 is a metabolic disorder resulting in myopathy characterized by exercise intolerance, cramps, muscle weakness and recurrent myoglobinuria.
  • 序列相似性Belongs to the glycogen phosphorylase family.
  • 翻译后修饰Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Glycogen phosphorylase antibody
    • Glycogen phosphorylase muscle form antibody
    • muscle form antibody
    • Muscpho antibody
    • Myophosphorylase antibody
    • Phosphorylase glycogen muscle (McArdle syndrome glycogen storage disease type V) antibody
    • Pygm antibody
    • PYGM_HUMAN antibody
    see all

Anti-PYGM antibody 图像

  • ab60982, at a concentration of 20µg/ml, staining PYGM in formalin fixed paraffin embedded human skeletal muscle tissue sections by Immunohistochemistry.

Anti-PYGM antibody (ab60982)参考文献

ab60982 has not yet been referenced specifically in any publications.

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