Anti-PYGL抗体(ab61013)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to PYGL
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide corresponding to Human PYGL (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH).

  • 阳性对照
    • Human liver

性能

应用

Our Abpromise guarantee covers the use of ab61013 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use a concentration of 10 µg/ml.

靶标

  • 功能
    Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  • 疾病相关
    Defects in PYGL are the cause of glycogen storage disease type 6 (GSD6) [MIM:232700]. A metabolic disorder characterized by mild to moderate hypoglycemia, mild ketosis, growth retardation, and prominent hepatomegaly. Heart and skeletal muscle are not affected.
  • 序列相似性
    Belongs to the glycogen phosphorylase family.
  • 翻译后修饰
    Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Glycogen phosphorylase antibody
    • Glycogen phosphorylase L antibody
    • Glycogen phosphorylase liver antibody
    • Glycogen phosphorylase liver form antibody
    • GSD6 antibody
    • Hers disease, glycogen storage disease type VI antibody
    • liver form antibody
    • OTTHUMP00000233649 antibody
    • OTTHUMP00000233651 antibody
    • Phosphorylase glycogen liver antibody
    • Pygl antibody
    • PYGL_HUMAN antibody
    see all

图片

  • ab61013 at 10µg/ml staining formalin fixed paraffin embedded liver tissue.

文献

ab61013 has not yet been referenced specifically in any publications.

客户评价及客户问答

Unfortunately due to proprietary reasons I would not be able to provide you the exact sequence but I aligned the human sequence P06737 and the mouse sequence Q9ET01. The immunogenic peptide for antibody LS-A2283 has 80% homology between the human and t...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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