Anti-PYGL抗体(ab103419)

概述

  • 产品名称
  • 描述
    兔多克隆抗体to PYGL
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length Human PYGL (NP_002854.3, amino acids 1-847).

  • 阳性对照
    • Human liver tissue lysate; PYGL transfected 293T cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab103419 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 97 kDa.

靶标

  • 功能
    Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
  • 疾病相关
    Defects in PYGL are the cause of glycogen storage disease type 6 (GSD6) [MIM:232700]. A metabolic disorder characterized by mild to moderate hypoglycemia, mild ketosis, growth retardation, and prominent hepatomegaly. Heart and skeletal muscle are not affected.
  • 序列相似性
    Belongs to the glycogen phosphorylase family.
  • 翻译后修饰
    Phosphorylation of Ser-15 converts phosphorylase B (unphosphorylated) to phosphorylase A.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Glycogen phosphorylase antibody
    • Glycogen phosphorylase L antibody
    • Glycogen phosphorylase liver antibody
    • Glycogen phosphorylase liver form antibody
    • GSD6 antibody
    • Hers disease, glycogen storage disease type VI antibody
    • liver form antibody
    • OTTHUMP00000233649 antibody
    • OTTHUMP00000233651 antibody
    • Phosphorylase glycogen liver antibody
    • Pygl antibody
    • PYGL_HUMAN antibody
    see all

图片

  • Anti-PYGL antibody (ab103419) at 5 µg/ml + Human liver tissue lysate at 50 µg

    Predicted band size : 97 kDa
  • All lanes : Anti-PYGL antibody (ab103419) at 5 µg/ml

    Lane 1 : PYGL transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 97 kDa

实验方案

文献

ab103419 has not yet been referenced specifically in any publications.

客户评价及客户问答

The PYGL antibody ab103419 is raised against the full-length protein, amino acids 1-847. The sequence is described in the UniProt entry, accession P06737. Here is a link to the entry. http://www.uniprot.org/uniprot/P06737.

It is a polyclonal a...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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