概述

  • 产品名称Anti-PXK抗体
    参阅全部 PXK 一抗
  • 描述
    兔多克隆抗体to PXK
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    KLH conjugated synthetic peptide selected from the center-terminal region of human PXK.

  • 阳性对照
    • Hela cell line lysate.

性能

应用

Our Abpromise guarantee covers the use of ab71397 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
ELISA
  • 应用说明ELISA: 1/1000.
    WB: 1/100 - 1/500. Detects bands of approximately 50 and 75 kDa (predicted molecular weight: 44 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity.
    • 组织特异性Widely expressed in all tissues examined except in heart. Isoform 1 is expressed in high levels in the brain, skeletal muscle, spleen and testis. Isoform 7 expression has yet to be demonstrated.
    • 序列相似性Belongs to the protein kinase superfamily.
      Contains 1 protein kinase domain.
      Contains 1 PX (phox homology) domain.
      Contains 1 WH2 domain.
    • 结构域The protein kinase domain is predicted to be catalytically inactive.
    • 细胞定位Cytoplasm. Cell membrane. Also associates with the plasma membrane. Isoform 3 is present throughout the cell.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ20335 antibody
      • K-ATPase antibody
      • Modulator of Na antibody
      • Modulator of Na K ATPase antibody
      • Modulator of Na K ATPase long form antibody
      • MONaKA antibody
      • PX domain containing protein kinase like protein antibody
      • PX domain containing serine/threonine kinase antibody
      • PX domain-containing protein kinase-like protein antibody
      • PX ser/thr kinase v2 antibody
      • PX serine/threonine kinase antibody
      • Pxk antibody
      • PXK_HUMAN antibody
      see all

    Anti-PXK antibody 图像

    • Anti-PXK antibody (ab71397) at 1/60 dilution + Hela cell line lysate at 35 µg

      Predicted band size : 44 kDa
      Observed band size : 50 kDa (why is the actual band size different from the predicted?)
      Additional bands at : 75 kDa. We are unsure as to the identity of these extra bands.

    Anti-PXK antibody (ab71397)参考文献

    ab71397 has not yet been referenced specifically in any publications.

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