The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
应用说明Peptide ELISA: Use at an assay dependent dilution. Antibody detection limit dilution: 1/16000.
WB: Use at a concentration of 0.5 - 1.5 µg/ml. Detects a band of approximately 110 kDa (predicted molecular weight: 106 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
功能Implicated in neuroendocrine secretory processes. May be involved in processes specific for neurosecretory granules, such as their biogenesis, trafficking or regulated exocytosis or may have a general role in neuroendocrine functions. Seems to lack intrinsic enzyme activity. May play a role in the regulation of secretory granules via its interaction with SNTB2.
组织特异性Expression is restricted to neuroendocrine cells. Found in pancreas, brain and pituitary.
序列相似性Belongs to the protein-tyrosine phosphatase family. Receptor class 8 subfamily. Contains 1 tyrosine-protein phosphatase domain.
翻译后修饰Appears to undergo multiple proteolytic cleavage at consecutive basic residues.