概述

  • 产品名称Anti-PTP4A3抗体
    参阅全部 PTP4A3 一抗
  • 描述
    兔多克隆抗体to PTP4A3
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein (Human)

性能

应用

Our Abpromise guarantee covers the use of ab26947 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/5000. Predicted molecular weight: 19 kDa.
ELISA 1/100000.

靶标

  • 功能Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II.
  • 组织特异性Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis.
  • 序列相似性Belongs to the protein-tyrosine phosphatase family.
    Contains 1 tyrosine-protein phosphatase domain.
  • 翻译后修饰Farnesylated. Farnesylation is required for membrane targeting.
  • 细胞定位Cell membrane. Early endosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Potentially prenylated protein tyrosine phosphatase antibody
    • PRL 3 antibody
    • PRL R antibody
    • PRL-3 antibody
    • PRL-R antibody
    • PRL3 antibody
    • PRLR antibody
    • Protein tyrosine phosphatase 4a3 antibody
    • Protein tyrosine phosphatase type IVA 3 antibody
    • Protein-tyrosine phosphatase 4a3 antibody
    • Protein-tyrosine phosphatase of regenerating liver 3 antibody
    • PTP 4A3 antibody
    • PTP4A3 antibody
    • TP4A3_HUMAN antibody
    see all

Anti-PTP4A3 antibody 图像

  • All lanes : Anti-PTP4A3 antibody (ab26947) at 1/5000 dilution

    Lane 1 : (T2.5) IPTG induction of the recombinant protein expression for 2.5 hours.
    Lane 2 : (T0) before IPTG induction of the protein expression


    Predicted band size : 19 kDa
    Observed band size : 23.9 kDa (why is the actual band size different from the predicted?)

Anti-PTP4A3 antibody (ab26947)参考文献

This product has been referenced in:
  • Laurent C  et al. High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients. Cancer Res 71:666-74 (2011). WB ; Human . Read more (PubMed: 21135111) »

See 1 Publication for this product

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