Anti-PTP4A3/PRL-R抗体(ab26947)
Key features and details
- Rabbit polyclonal to PTP4A3/PRL-R
- Suitable for: WB
- Reacts with: Recombinant fragment
- Isotype: IgG
概述
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产品名称
Anti-PTP4A3/PRL-R抗体
参阅全部 PTP4A3/PRL-R 一抗 -
描述
兔多克隆抗体to PTP4A3/PRL-R -
宿主
Rabbit -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Recombinant fragment -
免疫原
Recombinant full length protein corresponding to Human PTP4A3/PRL-R.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
Constituent: Whole serum -
Concentration information loading...
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纯度
Whole antiserum -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab26947于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/5000. Predicted molecular weight: 19 kDa.
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说明 |
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WB
1/5000. Predicted molecular weight: 19 kDa. |
靶标
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功能
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis. May be involved in the progression of cardiac hypertrophy by inhibiting intracellular calcium mobilization in response to angiotensin II. -
组织特异性
Mainly expressed in cardiomyocytes and skeletal muscle; also found in pancreas. Consistently overexpressed in colon cancer metastasis. -
序列相似性
Belongs to the protein-tyrosine phosphatase family.
Contains 1 tyrosine-protein phosphatase domain. -
翻译后修饰
Farnesylated. Farnesylation is required for membrane targeting. -
细胞定位
Cell membrane. Early endosome. - Information by UniProt
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别名
- Potentially prenylated protein tyrosine phosphatase antibody
- PRL 3 antibody
- PRL R antibody
see all
图片
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All lanes : Anti-PTP4A3/PRL-R antibody (ab26947) at 1/5000 dilution
Lane 1 : (T2.5) IPTG induction of the recombinant protein expression for 2.5 hours.
Lane 2 : (T0) before IPTG induction of the protein expression
Predicted band size: 19 kDa
Observed band size: 23.9 kDa why is the actual band size different from the predicted?
数据表及文件
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Datasheet download
文献 (1)
ab26947 被引用在 1 文献中.
- Laurent C et al. High PTP4A3 Phosphatase Expression Correlates with Metastatic Risk in Uveal Melanoma Patients. Cancer Res 71:666-74 (2011). WB ; Human . PubMed: 21135111