概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 序列CFKDSNGHRNN

技术指标

Our Abpromise guarantee covers the use of ab45609 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • HH 72
    • HH72
    • Hypothetical protein DKFZp779M0721
    • Phosphatase of regenerating liver 1
    • PRL 1
    • PRL-1
    • PRL1
    • Protein tyrosine phosphatase PTPCAAX1
    • Protein tyrosine phosphatase type IVA 1
    • Protein tyrosine phosphatase type IVA member 1
    • Protein-tyrosine phosphatase 4a1
    • Protein-tyrosine phosphatase of regenerating liver 1
    • Protein-tyrosine phosphatase, type 4A, 1
    • PTP(CAAXI)
    • Ptp4a1
    • PTPCAAX1
    • TP4A1_HUMAN
    see all
  • 功能Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.
  • 组织特异性Expressed in bone marrow, lymph nodes, T lymphocytes, spleen, thymus and tonsil. Overexpressed in tumor cell lines.
  • 序列相似性Belongs to the protein-tyrosine phosphatase family.
    Contains 1 tyrosine-protein phosphatase domain.
  • 发展阶段Expressed in fetal liver.
  • 翻译后修饰Farnesylated. Farnesylation is required for membrane targeting. Unfarnesylated forms are shifted into the nucleus.
  • 细胞定位Cell membrane. Early endosome. Endoplasmic reticulum. Cytoplasm. Cytoplasm > cytoskeleton > spindle. And mitotic spindle.
  • Information by UniProt

PTP4A1 peptide (ab45609)参考文献

ab45609 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab45609.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"