概述

  • 产品名称Anti-PTOP抗体
    参阅全部 PTOP 一抗
  • 描述
    兔多克隆抗体to PTOP
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse
    预测可用于: Rat, Horse, Guinea pig, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 351-400 (PRTSAQELCS VWEPPERHRD TSAFQYKYET PSASLHTQVQ TARLSPQLVA) of Mouse PTOP (NP_001012656).

  • 阳性对照
    • Mouse muscle tissue lysate.

性能

应用

Our Abpromise guarantee covers the use of ab104297 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 58 kDa. Mouse protein 45kD Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomer elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a role in organogenesis.
  • 细胞定位Nucleus. Chromosome > telomere.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Acd antibody
    • ACD_HUMAN antibody
    • Adrenocortical dysplasia homolog antibody
    • Adrenocortical dysplasia protein homolog antibody
    • PIP1 antibody
    • POT1 and TIN2 organizing protein antibody
    • POT1 and TIN2-interacting protein antibody
    • TIN2 interacting protein 1 antibody
    • TINT1 antibody
    • TPP1 antibody
    see all

Anti-PTOP antibody 图像

  • Anti-PTOP antibody (ab104297) at 1 µg/ml + Mouse muscle tissue lysate at 10 µg

    Predicted band size : 58 kDa

Anti-PTOP antibody (ab104297)参考文献

ab104297 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab104297.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"