概述

  • 产品名称Anti-PTGES2抗体
    参阅全部 PTGES2 一抗
  • 描述
    小鼠单克隆抗体to PTGES2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 270-378 of Human PTGES2

性能

应用

Our Abpromise guarantee covers the use of ab57769 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.

    This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Isomerase that catalyzes the conversion of unstable intermediate of prostaglandin E2 H2 (PGH2) into the more stable prostaglandin E2 (PGE2) form. May also have transactivation activity toward IFN-gamma (IFNG), possibly via an interaction with CEBPB; however, the relevance of transcription activation activity remains unclear.
    • 组织特异性Widely expressed. Expressed in the heart, including apex, inter-ventricular septum, both atria and ventricles, but not in the aorta. Also expressed in fetal heart. Detected in various regions of the brain: cerebellum; occipital, frontal and parietal lobes. Also expressed in the lymph nodes, skeletal muscle, kidney and trachea, but not in the thymus or lung. Overexpressed in colorectal cancer.
    • 通路Lipid metabolism; prostaglandin biosynthesis.
    • 序列相似性Belongs to the GST superfamily.
      Contains 1 glutaredoxin domain.
      Contains 1 GST C-terminal domain.
    • 细胞定位Golgi apparatus membrane and Cytoplasm > perinuclear region. Synthetized as a Golgi membrane-bound protein, which is further cleaved into the predominant soluble truncated form. The truncated form is cytoplasmic and is enriched in the perinuclear region.
    • Information by UniProt
    • 数据库链接
    • 别名
      • C9orf15 antibody
      • FLJ14038 antibody
      • Gamma interferon activated transcriptional element binding factor 1 antibody
      • GATE binding factor 1 antibody
      • GBF 1 antibody
      • GBF1 antibody
      • Membrane associated prostaglandin E synthase 2 antibody
      • MGC11289 antibody
      • Microsomal prostaglandin E synthase 2 antibody
      • mPGES 2 antibody
      • mPGES-2 antibody
      • PGES2 antibody
      • PGES2_HUMAN antibody
      • Prostaglandin E synthase 2 antibody
      • Prostaglandin E synthase 2 truncated form antibody
      • PTGES 2 antibody
      • PTGES2 antibody
      see all

    Anti-PTGES2 antibody 图像

    • Western blot against tagged recombinant protein immunogen using ab57769 PTGES2 antibody at 1ug/ml. Predicted band size of immunogen is 38 kDa

    Anti-PTGES2 antibody (ab57769)参考文献

    ab57769 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57769.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"