概述

  • 产品名称Anti-PTBP1抗体
    参阅全部 PTBP1 一抗
  • 描述
    小鼠单克隆抗体to PTBP1
  • 经测试应用适用于: WB, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: KKFKGDSRSA GVPSRVIHIR KLPIDVTEGE VISLGLPFGK VTNLLMLKGK NQAFIEMNTE EAANTMVNYY TSVTPVLRGQ PIYIQFSNHK ELKTDSSPNQ , corresponding to amino acids 45-145 of Human PTBP1

性能

应用

Our Abpromise guarantee covers the use of ab58131 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 3 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA.
    • 序列相似性Contains 4 RRM (RNA recognition motif) domains.
    • 细胞定位Nucleus.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 57 kDa RNA binding protein PPTB 1 antibody
      • 57 kDa RNA-binding protein PPTB-1 antibody
      • Heterogeneous nuclear ribonucleoprotein I antibody
      • Heterogeneous Nuclear Ribonucleoprotein Polypeptide I antibody
      • hnRNP I antibody
      • HNRNP-I antibody
      • HNRNPI antibody
      • HNRPI antibody
      • MGC10830 antibody
      • MGC8461 antibody
      • Polypyrimidine tract binding protein (heterogeneous nuclear ribonucleoprotein I) antibody
      • Polypyrimidine Tract Binding Protein 1 antibody
      • Polypyrimidine tract binding protein antibody
      • Polypyrimidine tract-binding protein 1 antibody
      • pPTB antibody
      • PTB 1 antibody
      • PTB 2 antibody
      • PTB 3 antibody
      • PTB 4 antibody
      • PTB antibody
      • PTB T antibody
      • PTB1 antibody
      • PTB2 antibody
      • PTB3 antibody
      • PTB4 antibody
      • PTBP 1 antibody
      • PTBP1 antibody
      • PTBP1_HUMAN antibody
      • PTBT antibody
      • RNA Binding Protein antibody
      see all

    Anti-PTBP1 antibody 图像

    • PTBP1 antibody (ab58131) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human kidney.


    • Predicted band size : 57 kDa
      PTBP1 antibody (ab58131) at 1ug/lane + A-431 cell lysate at 25ug/lane.

    Anti-PTBP1 antibody (ab58131)参考文献

    This product has been referenced in:
    • Hope NR & Murray GI The expression profile of RNA-binding proteins in primary and metastatic colorectal cancer: relationship of heterogeneous nuclear ribonucleoproteins with prognosis. Hum Pathol 42:393-402 (2011). IHC-P ; Human . Read more (PubMed: 21194727) »

    See 1 Publication for this product

    Product Wall

    Thank you for your e-mail. We have not tested the cross reactivity between PTBP1 and PTBP2 or other products yet. We feel sorry that at this moment we have no information about their cross reactivity. Please feel free to contact me if I can provide fu...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"