概述

  • 产品名称Anti-PSME1抗体
    参阅全部 PSME1 一抗
  • 描述
    兔多克隆抗体to PSME1
  • 特异性Detects PSME1 (proteasome activator complex subunit 1).
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Hamster, Dog, Human
    预测可用于: Cow, Pig, Cynomolgus Monkey
  • 免疫原

    Synthetic peptide corresponding to Human PSME1 aa 5-22.
    Sequence:

    RVQPEAQAKVDVFREDLC


    (Peptide available as ab4949)

  • 阳性对照
    • Rat brain extract.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液Constituents: 0.1% BSA, 99% PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

相关产品

应用

Our Abpromise guarantee covers the use of ab3333 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 28 kDa (predicted molecular weight: 29 kDa).Can be blocked with PSME1 peptide (ab4949).

By Western blot, this antibody detects a 28 kDa protein representing PSME1 in rat brain extract.

靶标

  • 功能Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome.
  • 序列相似性Belongs to the PA28 family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 11S regulator complex alpha subunit antibody
    • 11S regulator complex subunit alpha antibody
    • 29 kD MCP activator subunit antibody
    • 29kD MCP activator subunit antibody
    • Activator of multicatalytic protease subunit 1 antibody
    • IFI5111 antibody
    • IGUP I-5111 antibody
    • Interferon gamma IEF SSP 5111 antibody
    • Interferon gamma inducible protein 5111 antibody
    • Interferon gamma up regulated I 5111 protein antibody
    • Interferon gamma up-regulated I-5111 protein antibody
    • MGC8628 antibody
    • PA28a antibody
    • PA28alpha antibody
    • Proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) antibody
    • Proteasome activator 28 subunit alpha antibody
    • Proteasome activator complex subunit 1 antibody
    • Proteasome activator subunit 1 antibody
    • PSME1 antibody
    • PSME1_HUMAN antibody
    • REG-alpha antibody
    • REGalpha antibody
    see all

Anti-PSME1 antibody 图像



  • Predicted band size : 29 kDa

    Western blot detection of PSME1 in Hepa 1 cell lysate using ab3333.

Anti-PSME1 antibody (ab3333)参考文献

This product has been referenced in:
  • Glogauer JE  et al. Neutrophils Increase Oral Squamous Cell Carcinoma Invasion through an Invadopodia-Dependent Pathway. Cancer Immunol Res 3:1218-26 (2015). Read more (PubMed: 26112922) »
  • Pla A  et al. TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain. Cell Death Dis 5:e1066 (2014). WB ; Mouse . Read more (PubMed: 24556681) »

See all 2 Publications for this product

Product Wall

Not to the best of my knoweldge. To eliminate all question, I would perform a BLAST search on the immunizing peptide.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"