概述

  • 产品名称Anti-PSMA7抗体
    参阅全部 PSMA7 一抗
  • 描述
    小鼠单克隆抗体to PSMA7
  • 经测试应用适用于: WB, ICC/IF, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein corresponding to Human PSMA7 aa 1-249.
    Database link: O14818

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2b
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab55626 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 28 kDa.
ICC/IF Use a concentration of 10 µg/ml.
IHC-P Use a concentration of 5 µg/ml.

靶标

  • 功能The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. Plays an important role in the regulation of cell proliferation or cell cycle control, transcriptional regulation, immune and stress response, cell differentiation, and apoptosis. Interacts with some important proteins involved in transcription factor regulation, cell cycle transition, viral replication and even tumor initiation and progression. Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
  • 序列相似性Belongs to the peptidase T1A family.
  • 翻译后修饰Phosphorylation by ABL1 or ABL2 leads to an inhibition of proteasomal activity and cell cycle transition blocks.
  • 细胞定位Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • C6 antibody
    • HSPC antibody
    • MGC3755 antibody
    • OTTHUMP00000031449 antibody
    • OTTHUMP00000031450 antibody
    • OTTHUMP00000031453 antibody
    • Proteasome (prosome macropain) subunit alpha type 7 antibody
    • Proteasome alpha 7 subunit antibody
    • Proteasome subunit alpha 4 antibody
    • Proteasome subunit alpha type 7 antibody
    • Proteasome subunit alpha type-7 antibody
    • Proteasome subunit RC6 1 antibody
    • Proteasome subunit RC6-1 antibody
    • Proteasome subunit XAPC7 antibody
    • PSA7_HUMAN antibody
    • PSMA 7 antibody
    • PSMA7 antibody
    • RC6 1 antibody
    • XAPC7 antibody
    see all

Anti-PSMA7 antibody 图像

  • PSMA7 antibody (ab55626) used in immunofluorescence at 1-5ug/ml on HeLa cells.
  • PSMA7 antibody (ab55626) used in immunohistochemistry at 5ug/ml on formalin fixed and paraffin embedded human colon tissue.


  • Predicted band size : 28 kDa
    PSMA7 antibody (ab55626) at 1ug/lane + HeLa cell lysate at 25ug/lane.

Anti-PSMA7 antibody (ab55626)参考文献

ab55626 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab55626.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"