Anti-PSD93抗体[S18-30] (ab94588)

概述

  • 产品名称Anti-PSD93抗体[S18-30]
    参阅全部 PSD93 一抗
  • 描述
    小鼠单克隆抗体[S18-30] to PSD93
  • 特异性No cross-reactivity against other MAGUK family members PSD95, SAP97, SAP102 expressed in transfected cells.
  • 经测试应用适用于: WB, IHC-P, IHC-Fr, ICC/IFmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Fusion protein, corresponding to amino acids 1 - 852 of Rat PSD93 (UniProt Q63622).

  • 阳性对照
    • Rat brain lysate

性能

应用

Our Abpromise guarantee covers the use of ab94588 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
IHC-P
IHC-Fr
ICC/IF
  • 应用说明ICC/IF: Use at a concentration of 0.1-1.0µg/mL (perox) or 1.0-10µg/mL (IF).
    IHC-P: Use at a concentration of 0.1-1.0µg/mL (perox) or 1.0-10µg/mL (IF).
    IHC-Fr: Use at a concentration of 0.1-1.0µg/mL (perox) or 1.0-10µg/mL (IF).
    WB: Use at a concentration of 1 - 10 µg/ml. Predicted molecular weight: 97 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.
    • 序列相似性Belongs to the MAGUK family.
      Contains 1 guanylate kinase-like domain.
      Contains 3 PDZ (DHR) domains.
      Contains 1 SH3 domain.
    • 结构域An N-terminally truncated L27 domain is predicted in isoform 2 at positions 1 through 27.
    • 翻译后修饰Palmitoylation of isoform 1 is not required for targeting to postsynaptic density.
    • 细胞定位Cell membrane. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Membrane. Cell projection, axon. Concentrated in soma and postsynaptic density of a subset of neurons.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Channel associated protein of synapse 110 antibody
      • Channel associated protein of synapses 110kD antibody
      • Channel-associated protein of synapse-110 antibody
      • Chapsyn 110 antibody
      • Chapsyn-110 antibody
      • Chapsyn110 antibody
      • Discs, large homolog 2 (Drosophila) antibody
      • Disks large homolog 2 antibody
      • DKFZp781D1854 antibody
      • DKFZp781E0954 antibody
      • Dlg 2 antibody
      • dlg2 antibody
      • DLG2_HUMAN antibody
      • Dlgh 2 antibody
      • Dlgh2 antibody
      • FLJ37266 antibody
      • Gm1197 antibody
      • MGC131811 antibody
      • Postsynaptic density protein PSD 93 antibody
      • Postsynaptic density protein PSD-93 antibody
      • Postsynaptic density protein PSD93 antibody
      • PSD 93 antibody
      • PSD93 antibody
      see all

    Anti-PSD93 antibody [S18-30] 图像



    • Predicted band size : 97 kDa
      Western blot detection of PSD93 in Rat brain membrane lysates using ab94588 at 1:1000 dilution.

    Anti-PSD93 antibody [S18-30] (ab94588)参考文献

    ab94588 has not yet been referenced specifically in any publications.

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