概述

  • 产品名称
    Anti-PSCA抗体, prediluted
    参阅全部 PSCA 一抗
  • 描述
    兔多克隆抗体to PSCA, prediluted
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (Human) (extracellular).

  • 阳性对照
    • Bladder carcinoma and Prostate carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab15169 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明
    IHC-P: Ready to use. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

    Not tested in other applications.
  • 靶标

    • 相关性
      PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
    • 细胞定位
      Cell membrane; Lipid-anchor, GPI-anchor.
    • 数据库链接
    • 别名
      • PRO 232 antibody
      • PRO232 antibody
      • Prostate stem cell antigen antibody

    图片

    • ab15169 staining PSCA in human breast carcinoma by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

    文献

    This product has been referenced in:
    • Taeb J  et al. Expression of prostate stem cell antigen (PSCA) in prostate cancer: A tissue microarray study of Iranian patients. Pathol Res Pract N/A:N/A (2013). IHC-P ; Human . Read more (PubMed: 24183365) »

    See 1 Publication for this product

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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