概述

  • 产品名称Anti-PSCA抗体
    参阅全部 PSCA 一抗
  • 描述
    兔多克隆抗体to PSCA
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (unfortunately, the amino acid sequence is considered to be commercially sensitive) (Human) (extracellular).

  • 阳性对照
    • Bladder carcinoma and Prostate carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab15168 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/75. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.

靶标

  • 相关性PSCA (Prostate Stem Cell antigen) is a cell surface antigen, which is overexpressed in ~40% of primary prostate cancers and in as many as 100% of metastatic ones. PSCA is also overexpressed in a majority of transitional cell and pancreatic carcinomas. Antibody directed against PSCA inhibits tumorigenesis, slows tumor growth, prolongs survival and prevents metastasis in a preclinical zenograft model indicating that PSCA may have utility as a prognostic marker and/or therapeutic target in prostate cancer.
  • 细胞定位Cell membrane; Lipid-anchor, GPI-anchor.
  • 数据库链接
  • 别名
    • PRO 232 antibody
    • PRO232 antibody
    • Prostate stem cell antigen antibody

Anti-PSCA antibody 图像

  • ab15168 staining PSCA in human breast carcinoma by Immunohistochemistry (Formalin/ PFA fixed paraffin embedded tissue sections).

Anti-PSCA antibody (ab15168)参考文献

This product has been referenced in:
  • Smith C  et al. Lack of association between the rs2294008 polymorphism in the prostate stem cell antigen gene and colorectal neoplasia: a case-control and immunohistochemical study. BMC Res Notes 5:371 (2012). IHC-P ; Human . Read more (PubMed: 22824379) »

See 1 Publication for this product

Product Wall

Antigen retrieval protocol: 1. Put tissue slides in 1X citrate buffer pH 6.0(we usually use 300ml container with 250ml buffer). 2. Microwave at high power for several minutes(one container for 2 and half minutes, two containers for 4 and half minutes...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"