参阅全部 PRUNE 一抗
WB, ICC/IFmore details
Full length human PRUNE protein (NP_067045.1).
- WB: Raw 264.7 cell lysate, NIH/3T3 cell lysate, and PRUNE transfected 293T cell lysate
ICC/IF: HeLa cell
- 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- 存储溶液Preservative: None
Constituents: 1X PBS, pH 7.2
Concentration information loading...
- 纯度Protein A purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
||Use a concentration of 1 µg/ml. Predicted molecular weight: 50 kDa.
||Use a concentration of 10 µg/ml.
- 功能Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1.
- 组织特异性Ubiquitously expressed. Seems to be overexpressed in aggressive sarcoma subtypes, such as leiomyosarcomas and malignant fibrous histiocytomas (MFH) as well as in the less malignant liposarcomas.
- 序列相似性Belongs to the PPase class C family. Prune subfamily.
- 细胞定位Cytoplasm. Nucleus. Cell junction > focal adhesion. In some transfected cells a nuclear staining is also observed.
Information by UniProt
- DRES-17 antibody
- DRES17 antibody
- Drosophila-related expressed sequence 17 antibody
Anti-PRUNE antibody (ab88613)参考文献
has not yet been referenced specifically in any publications.
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