概述

  • 产品名称Anti-PRSS1抗体
    参阅全部 PRSS1 一抗
  • 描述
    兔多克隆抗体to PRSS1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within C terminal amino acids 184-233 (FCVGFLEGGK DSCQGDSGGP VVCNGQLQGV VSWGDGCAQK NKPGVYTKVY) of Human PRSS1 (NP_002760).

  • 阳性对照
    • HT1080 cell lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Constituents: 98% PBS, 2% Sucrose
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种��IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab115953 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 27 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these substrates.
  • 疾病相关Defects in PRSS1 are a cause of hereditary pancreatitis (HPC) [MIM:167800]; also known as chronic pancreatitis (CP). HPC is an autosomal dominant disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks.
  • 序列相似性Belongs to the peptidase S1 family.
    Contains 1 peptidase S1 domain.
  • 翻译后修饰Occurs in a single-chain form and a two-chain form, produced by proteolytic cleavage after Arg-122.
  • 细胞定位Secreted > extracellular space.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Alpha-trypsin chain 2 antibody
    • Beta-trypsin antibody
    • Cationic trypsinogen antibody
    • Digestive zymogen antibody
    • Nonfunctional trypsin 1 antibody
    • Prss1 antibody
    • Serine protease 1 antibody
    • TCR V beta 4.1 antibody
    • TRP1 antibody
    • TRY1 antibody
    • TRY1_HUMAN antibody
    • TRY4 antibody
    • TRYP1 antibody
    • Trypsin I antibody
    • Trypsinogen 1 antibody
    • Trypsinogen A antibody
    see all

Anti-PRSS1 antibody 图像

  • Anti-PRSS1 antibody (ab115953) at 1 µg/ml + HT1080 cell lysate at 10 µg

    Predicted band size : 27 kDa

Anti-PRSS1 antibody (ab115953)参考文献

ab115953 has not yet been referenced specifically in any publications.

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