• 产品名称
  • 描述
    山羊多克隆抗体to PRPF31
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Dog
  • 免疫原

    Synthetic peptide: LKVKGEKSGLMST, corresponding to C terminal amino acids 487-499 of Human PRPF31.

  • 阳性对照
    • A431 lysate.
  • 常规说明
    Principal Names - PRPF31; PRP31 pre-mRNA processing factor 31 homolog (yeast); RP11; PRP31; NY-BR-99; DKFZp566J153; pre-mRNA processing factor 31 homolog (yeast). Official Gene Symbol - PRPF31. GenBank Accession Number – NP_056444. LocusLink ID - 26121.



Our Abpromise guarantee covers the use of ab2467 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 62 kDa (predicted molecular weight: 55 kDa).Can be blocked with Human PRPF31 peptide (ab22909).


  • 功能
    Involved in pre-mRNA splicing. Required for U4/U6.U5 tri-snRNP formation.
  • 组织特异性
    Ubiquitously expressed.
  • 疾病相关
    Defects in PRPF31 are the cause of retinitis pigmentosa type 11 (RP11) [MIM:600138]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP11 inheritance is autosomal dominant.
  • 序列相似性
    Belongs to the PRP31 family.
    Contains 1 Nop domain.
  • 结构域
    Interacts with the snRNP via the Nop domain.
    The coiled coil domain is formed by two non-contiguous helices.
  • 细胞定位
    Nucleus speckle. Nucleus > Cajal body. Predominantly found in speckles and in Cajal bodies.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp566J153 antibody
    • hPrp 31 antibody
    • hPrp31 antibody
    • NY BR 99 antibody
    • Pre mRNA processing factor 31 antibody
    • Pre mRNA processing factor 31 homolog (yeast) antibody
    • Pre mRNA processing factor 31 homolog antibody
    • Pre-mRNA-processing factor 31 antibody
    • Precursor mRNA-processing factor 31, S. cerevisiae, homolog of antibody
    • Protein 61K antibody
    • PRP 31 antibody
    • PRP31 antibody
    • PRP31 pre mRNA processing factor 31 homolog (yeast) antibody
    • PRP31 pre mRNA processing factor 31 homolog antibody
    • PRP31_HUMAN antibody
    • PRPF 31 antibody
    • prpf31 antibody
    • RP 11 antibody
    • RP11 antibody
    • Serologically defined breast cancer antigen NY BR 99 antibody
    • Serologically defined breast cancer antigen NY-BR-99 antibody
    • SNRNP61 antibody
    • U4/U6 small nuclear ribonucleoprotein Prp31 antibody
    • U4/U6 snRNP 61 kDa protein antibody
    see all


Anti-PRPF31 antibody (ab2467)参考文献

ab2467 has not yet been referenced specifically in any publications.

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