Anti-Protocadherin 21抗体(ab108234)

概述

  • 产品名称Anti-Protocadherin 21抗体
    参阅全部 Protocadherin 21 一抗
  • 描述
    兔多克隆抗体to Protocadherin 21
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within N terminal amino acids 51-100 (

    GSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPTFGNITLVEELDRER

    ) of Human PCDH21 (NP_149091).

  • 阳性对照
    • Fetal heart lysate

性能

应用

Our Abpromise guarantee covers the use of ab108234 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 91 kDa (predicted molecular weight: 94 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能Potential calcium-dependent cell-adhesion protein. May be required for the structural integrity of the outer segment (OS) of photoreceptor cells.
  • 序列相似性Contains 6 cadherin domains.
  • 翻译后修饰Undergoes proteolytic cleavage; produces a soluble 95 kDa N-terminal fragment and a 25 kDa cell-associated C-terminal fragment.
  • 细胞定位Cell membrane. Localized at the junction between the inner and outer segments of rod and cone photoreceptors cells. Confined to the base of the OS. Localized on the edges of nascent evaginating disks on the side of the OS opposite the connecting cilium. Expressed at postnatal day 2 at the apical tip of the rod photoreceptor cells, the site of the developing OS. Colocalized with rhodopsin between postnatal days 2 and 9 at the base of the growing OS region.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cadherin-related family member 1 antibody
    • CDHR1 antibody
    • CDHR1_HUMAN antibody
    • CORD15 antibody
    • DKFZp434A132 antibody
    • KIAA1775 antibody
    • MT protocadherin antibody
    • PCDH 21 antibody
    • PCDH21 antibody
    • PCDH21 protein antibody
    • Photoreceptor cadherin antibody
    • prCAD antibody
    • Protocadherin-21 antibody
    • RP65 antibody
    see all

Anti-Protocadherin 21 antibody 图像

  • Anti-Protocadherin 21 antibody (ab108234) at 1 µg/ml + Fetal heart lysate at 10 µg

    Predicted band size : 94 kDa

Anti-Protocadherin 21 antibody (ab108234)参考文献

ab108234 has not yet been referenced specifically in any publications.

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