Anti-Protein phosphatase 1抑制剂subunit 2抗体(ab73948)
Key features and details
- Rabbit polyclonal to Protein phosphatase 1 inhibitor subunit 2
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-Protein phosphatase 1抑制剂subunit 2抗体
参阅全部 Protein phosphatase 1 inhibitor subunit 2 一抗 -
描述
兔多克隆抗体to蛋白phosphatase 1抑制剂subunit 2 -
宿主
Rabbit -
经测试应用
适用于: WB, IHC-Pmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Rat -
免疫原
Synthetic non-phosphopeptide derived from human Protein phosphatase 1 inhibitor subunit 2 around the phosphorylation site of serine 120 and serine 121 (Q-E-SP-SP-G-E).
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阳性对照
- Human breast carcinoma tissue. Extracts from Jurkat cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+ -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab73948于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 23 kDa).
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IHC-P |
1/50 - 1/100.
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说明 |
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WB
1/500 - 1/1000. Detects a band of approximately 25 kDa (predicted molecular weight: 23 kDa). |
IHC-P
1/50 - 1/100. |
靶标
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功能
Inhibitor of protein-phosphatase 1. -
序列相似性
Belongs to the protein phosphatase inhibitor 2 family. -
翻译后修饰
Phosphorylation on Thr-73 by GSK3 activates PP1 by dissociating the PP1-PPP1R2 complex (By similarity). Phosphorylation on Ser-44 by ATM activates PP1 by dissociating the PP1-PPP1R2 complex. - Information by UniProt
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数据库链接
- Entrez Gene: 5504 Human
- Entrez Gene: 66849 Mouse
- Entrez Gene: 192361 Rat
- Omim: 601792 Human
- SwissProt: P41236 Human
- SwissProt: Q9DCL8 Mouse
- SwissProt: P50411 Rat
- Unigene: 535731 Human
see all -
别名
- IPP 2 antibody
- IPP-2 antibody
- IPP2 antibody
see all
图片
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All lanes : Anti-Protein phosphatase 1 inhibitor subunit 2 antibody (ab73948) at 1/500 dilution
Lane 1 : Extracts from Jurkat cells
Lane 2 : Extracts from Jurkat cells with immunising peptide at 5 µg
Lysates/proteins at 5 µg per lane.
Predicted band size: 23 kDa
Observed band size: 25 kDa why is the actual band size different from the predicted? -
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using ab73948, at 1/50 dilution, in the presence (right panel) or absence (left panel) of immunising peptide.
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab73948 尚未被引用在任何文献中。