Anti-Protein Kinase D2抗体(ab118639)

概述

  • 产品名称Anti-Protein Kinase D2抗体
    参阅全部 Protein Kinase D2 一抗
  • 描述
    兔多克隆抗体to Protein Kinase D2
  • 特异性ab118639 detects endogenous levels of total Protein Kinase D2 protein.
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat
  • 免疫原

    Synthetic peptide conjugated to KLH, from the C terminus of Human Protein Kinase D2 (NP_057541.2).

  • 阳性对照
    • Human Heart, Human Brain Cerebellum and Human Intestine tissues. NIH 3T3 cell extracts.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 49% PBS, 0.88% Sodium chloride, 50% Glycerol
    Note: PBS without Mg2+, Ca2+
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab118639 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 97 kDa.
ELISA 1/5000.
IHC-P Use a concentration of 10 µg/ml.

靶标

  • 功能Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress.
  • 组织特异性Widely expressed.
  • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PKD subfamily.
    Contains 1 PH domain.
    Contains 2 phorbol-ester/DAG-type zinc fingers.
    Contains 1 protein kinase domain.
  • 翻译后修饰Phosphorylation of Ser-876 correlates with the activation status of the kinase.
    Ser-706 is probably phosphorylated by PKC.
  • 细胞定位Cytoplasm. Membrane. Translocation to the cell membrane is required for kinase activation.
  • Information by UniProt
  • 数据库链接
  • 别名
    • DKFZp586E0820 antibody
    • HSPC187 antibody
    • KPCD2_HUMAN antibody
    • nPKC D2 antibody
    • nPKC-D2 antibody
    • PKD2 antibody
    • PRKD 2 antibody
    • Prkd2 antibody
    • Protein kinase D2 antibody
    • Serine/threonine protein kinase D2 antibody
    • Serine/threonine-protein kinase D2 antibody
    see all

Anti-Protein Kinase D2 antibody 图像

  • ab118639 at 10 µg/ml staining Protein Kinase D2 in Formalin-Fixed, Paraffin-Embedded Human Brain Cerebellum tissue by Immunohistochemistry.
  • ab118639 at 10 µg/ml staining Protein Kinase D2 in Formalin-Fixed, Paraffin-Embedded Human Heart tissue by Immunohistochemistry.
  • ab118639 at 10 µg/ml staining Protein Kinase D2 in Formalin-Fixed, Paraffin-Embedded Human Intestine tissue by Immunohistochemistry.
  • All lanes : Anti-Protein Kinase D2 antibody (ab118639) at 1/500 dilution

    Lane 1 : NIH 3T3 cell extract, treated with PMA 250ng/ml for 15 mins.
    Lane 2 : NIH 3T3 cell extract, treated with PMA 250ng/ml for 15 mins with synthesized peptide


    Predicted band size : 97 kDa

Anti-Protein Kinase D2 antibody (ab118639)参考文献

ab118639 has not yet been referenced specifically in any publications.

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