Anti-Prosurfactant Protein B抗体(ab101804)


  • 产品名称Anti-Prosurfactant Protein B抗体
    参阅全部 Prosurfactant Protein B 一抗
  • 描述
    兔多克隆抗体to Prosurfactant Protein B
  • 特异性Detects full length Prosurfactant Protein B (42 kDa). Is also expected to bind to mature form (aa 201-279, ~9 kDa).
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) corresponding to Human Prosurfactant Protein B aa 200-300 conjugated to Keyhole Limpet Haemocyanin (KLH).
    (Peptide available as ab116184)

  • 阳性对照
    • This antibody gave a positive signal in both WI38 and A549 whole cell lysates.



Our Abpromise guarantee covers the use of ab101804 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 42 kDa (predicted molecular weight: 42 kDa).


  • 功能Pulmonary surfactant-associated proteins promote alveolar stability by lowering the surface tension at the air-liquid interface in the peripheral air spaces. SP-B increases the collapse pressure of palmitic acid to nearly 70 millinewtons per meter.
  • 疾病相关Pulmonary surfactant metabolism dysfunction 1
    Respiratory distress syndrome in premature infants
  • 序列相似性Contains 1 saposin A-type domain.
    Contains 3 saposin B-type domains.
  • 细胞定位Secreted, extracellular space, surface film.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 18 kDa pulmonary-surfactant protein antibody
    • 6 kDa protein antibody
    • PSP B antibody
    • PSPB antibody
    • PSPB_HUMAN antibody
    • Pulmonary surfactant apoprotein PSP-B antibody
    • Pulmonary surfactant-associated protein B antibody
    • Pulmonary surfactant-associated protein, 18-KD antibody
    • Pulmonary surfactant-associated proteolipid SPL(Phe) antibody
    • SFTB3 antibody
    • SFTP3 antibody
    • SFTPB antibody
    • SMDP1 antibody
    • SP B antibody
    • SP-B antibody
    • SPB antibody
    • surfactant protein B antibody
    • Surfactant, pulmonary-associated protein B antibody
    • surfactant-associated protein, pulmonary, 3 antibody
    see all

Anti-Prosurfactant Protein B antibody 图像

  • All lanes : Anti-Prosurfactant Protein B antibody (ab101804) at 1 µg/ml

    Lane 1 : WI-38 whole cell lysate (ab3960)
    Lane 2 : A549 (Human lung adenocarcinoma epithelial cell line) Whole Cell Lysate

    Lysates/proteins at 10 µg per lane.

    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 42 kDa
    Observed band size : 42 kDa
    Additional bands at : 39 kDa (possible cleavage fragment).

    Exposure time : 16 minutes

    The band observed at 39 kDa could potentially be a cleaved form of Prosurfactant Protein B due to the presence of a 24 amino acid signal peptide. Abcam recommends using milk as the blocking agent. Abcam welcomes customer feedback and would appreciate any comments regarding this product and the data presented above.

Anti-Prosurfactant Protein B antibody (ab101804)参考文献

ab101804 has not yet been referenced specifically in any publications.

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