Anti-Prostaglandin I2 Receptor抗体(ab123419)

概述

  • 产品名称
    Anti-Prostaglandin I2 Receptor抗体
    参阅全部 Prostaglandin I2 Receptor 一抗
  • 描述
    兔多克隆抗体to Prostaglandin I2 Receptor
  • 经测试应用
    适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 209-238 of Human Prostaglandin I2 Receptor (NP_000951.1, P43119).

  • 阳性对照
    • K562 cell line lysate

性能

应用

Our Abpromise guarantee covers the use of ab123419 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 41 kDa.

靶标

  • 功能
    Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
  • 序列相似性
    Belongs to the G-protein coupled receptor 1 family.
  • 翻译后修饰
    Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G(s) and signaling.
    Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C.
  • 细胞定位
    Cell membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • IP antibody
    • PGI receptor antibody
    • PGI2 receptor antibody
    • PI2R_HUMAN antibody
    • PRIPR antibody
    • Prostacyclin receptor antibody
    • Prostaglandin I2 (prostacyclin) receptor (IP) antibody
    • Prostaglandin I2 receptor antibody
    • Prostanoid IP receptor antibody
    • Ptgir antibody
    see all

图片

  • Anti-Prostaglandin I2 Receptor antibody (ab123419) at 1/100 dilution + K562 cell line lysate at 35 µg

    Predicted band size : 41 kDa

实验方案

文献

ab123419 has not yet been referenced specifically in any publications.

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