Anti-Prostaglandin E Receptor EP4抗体(ab45863)

概述

  • 产品名称Anti-Prostaglandin E Receptor EP4抗体
    参阅全部 Prostaglandin E Receptor EP4 一抗
  • 描述
    山羊多克隆抗体to Prostaglandin E Receptor EP4
  • 经测试应用适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Guinea pig, Dog, Chimpanzee, Baboon, Cynomolgus Monkey
  • 免疫原

    Synthetic peptide:

    C-LEREVSKNPDLQA

    , corresponding to Internal sequence amino acids 302-314 of Human Prostaglandin E Receptor EP4

  • 阳性对照
    • Human Testes lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 纯化说明Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab45863 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
WB
  • 应用说明Peptide ELISA: Antibody detection limit dilution 1:16,000.
    WB: Use at a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 55 kDa (predicted molecular weight: 53 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
    • 组织特异性High in intestine and in peripheral blood mononuclear cells; low in lung, kidney, thymus, uterus, vasculature and brain. Not found in liver, heart, retina oe skeletal muscle.
    • 序列相似性Belongs to the G-protein coupled receptor 1 family.
    • 细胞定位Cell membrane.
    • Information by UniProt
    • 数据库链接
    • 别名
      • EP 4 antibody
      • EP4 antibody
      • EP4R antibody
      • MGC126583 antibody
      • PE2R4_HUMAN antibody
      • PGE receptor EP4 subtype antibody
      • PGE2 receptor EP4 subtype antibody
      • Prostaglandin E receptor 4 antibody
      • Prostaglandin E receptor 4 subtype EP4 antibody
      • Prostaglandin E2 receptor antibody
      • Prostaglandin E2 receptor EP4 subtype antibody
      • Prostanoid EP4 receptor antibody
      • PTGER 2 antibody
      • PTGER 4 antibody
      • PTGER2 antibody
      • PTGER4 antibody
      see all

    Anti-Prostaglandin E Receptor EP4 antibody 图像

    • Anti-Prostaglandin E Receptor EP4 antibody (ab45863) at 0.1 µg/ml + Human Testes lysate (35µg protein in RIPA buffer)

      Predicted band size : 53 kDa
      Observed band size : 55 kDa (why is the actual band size different from the predicted?)

    Anti-Prostaglandin E Receptor EP4 antibody (ab45863)参考文献

    ab45863 has not yet been referenced specifically in any publications.

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