High affinity DP1 and CRTH2 receptor激动剂. Major prostaglandin produced by mast cells.
High affinity DP1 receptor agonist (Ki = 21 nM). Able to bind to the CRTH2 receptor (Ki = 2.4 nM). Major prostaglandin produced by mast cells in allergic disease. Capable of recruiting other inflammatory cells including eosinophils and basophils.
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
Soluble in ethanol to 100 mM and in DMSO to 100 mM
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.