Anti-Prostaglandin D Synthase (hematopoietic)抗体(ab23724)

概述

  • 产品名称Anti-Prostaglandin D Synthase (hematopoietic)抗体
    参阅全部 Prostaglandin D Synthase (hematopoietic) 一抗
  • 描述
    兔多克隆抗体to Prostaglandin D Synthase (hematopoietic)
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Rat
  • 免疫原

    Full length native protein (purified) (Rat).

  • 常规说明


    This antibody is specific for hematopoietic form PGD Synthase, and does not cross react with brain form of PGD Synthase.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • 存储溶液Preservative: 0.05% Sodium Azide
    Constituents: Whole serum
  • 纯度Whole antiserum
  • Primary antibody说明This antibody is specific for hematopoietic form PGD Synthase, and does not cross react with brain form of PGD Synthase.
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab23724 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/800. Predicted molecular weight: 22 kDa.
ELISA 1/800.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
  • 组织特异性Expressed in a number of megakaryocytic cell lines but not in platelets. Highly expressed in adipose tissue, macrophages and placenta. Also expressed at lower levels in lung, heart, lymph nodes, appendix, bone marrow and fetal liver.
  • 序列相似性Belongs to the GST superfamily. Sigma family.
    Contains 1 GST C-terminal domain.
    Contains 1 GST N-terminal domain.
  • 发展阶段Highest levels in immature megakaryocytic cells. Disappears after final differentiation to platelets.
  • 细胞定位Cytoplasm.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Cerebrin 28 antibody
    • Glutathione dependent PGD synthetase antibody
    • Glutathione S-transferase antibody
    • Glutathione-dependent PGD synthase antibody
    • Glutathione-requiring prostaglandin D synthase antibody
    • GST class-sigma antibody
    • H PGDS antibody
    • H-PGDS antibody
    • Haematopoietic prostaglandin D synthase antibody
    • Haematopoietic prostaglandin D2 synthase antibody
    • Hematopoietic prostaglandin D synthase antibody
    • Hpgds antibody
    • HPGDS_HUMAN antibody
    • Prostaglandin D synthase antibody
    • Prostaglandin D2 synthase hematopoietic antibody
    • Prostaglandin H2 D isomerase antibody
    • Prostaglandin-H2 D-isomerase antibody
    • PTGDS2 antibody
    see all

Anti-Prostaglandin D Synthase (hematopoietic) antibody (ab23724)参考文献

ab23724 has not yet been referenced specifically in any publications.

Product Wall

Application Western blot
Sample Rat Tissue lysate - other (Prefrontal Cortex)
Gel Running Conditions Reduced Denaturing
Loading amount 15 µg
Specification Prefrontal Cortex
Blocking step BSA as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
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提交于 Nov 19 2015

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