Anti-Properdin抗体[10-18] (ab58984)

概述

  • 产品名称Anti-Properdin抗体[10-18]
    参阅全部 Properdin 一抗
  • 描述
    小鼠单克隆抗体[10-18] to Properdin
  • 经测试应用适用于: ELISA, IHC-Fr, Functional Studiesmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Native purified Properdin from human serum.

  • 阳性对照
    • Histology positive control tissue: Kidney from post streptococcal glomerulonephritis patients.

性能

应用

Our Abpromise guarantee covers the use of ab58984 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
IHC-Fr
Functional Studies
  • 应用说明ELISA: Use at an assay dependent dilution.
    FuncS: Use at an assay dependent dilution.
    Note: This antibody inhibits the function of Properdin. Removal of sodium azide is recommended prior to use in functional assays
    IHC-Fr: Use at an assay dependent dilution.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能A positive regulator of the alternate pathway of complement. It binds to and stabilizes the C3- and C5-convertase enzyme complexes.
    • 疾病相关Defects in CFP are the cause of properdin deficiency (PFD) [MIM:312060]. PFD results in higher susceptibility to bacterial infections; especially to meningococcal infections. Three phenotypes have been reported: complete deficiency (type I), incomplete deficiency (type II), and dysfunction of properdin (type III).
    • 序列相似性Contains 6 TSP type-1 domains.
    • 细胞定位Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • BFD antibody
      • CFP antibody
      • Complement factor P antibody
      • Complement factor properdin antibody
      • Factor P antibody
      • PFC antibody
      • PFD antibody
      • PROP_HUMAN antibody
      • Properdin antibody
      • Properdin P factor complement antibody
      see all

    Anti-Properdin antibody [10-18] (ab58984)参考文献

    ab58984 has not yet been referenced specifically in any publications.

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