Anti-Prokineticin 2抗体(ab87360)


  • 产品名称Anti-Prokineticin 2抗体
    参阅全部 Prokineticin 2 一抗
  • 描述
    兔多克隆抗体to Prokineticin 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
    预测可用于: Macaque Monkey, Gorilla
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 100 to the C-terminus of Human Prokineticin 2.

  • 阳性对照
    • This antibody gave a positive signal in the following tissue lysates: Human Testis; Human Small Intestine; Mouse Testis; Rat Testis.



Our Abpromise guarantee covers the use of ab87360 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Detects a band of approximately 21 kDa (predicted molecular weight: 14 kDa).


  • 功能May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.
  • 组织特异性Expressed in the testis and, at low levels, in the small intestine.
  • 疾病相关Defects in PROK2 are the cause of Kallmann syndrome type 4 (KAL4) [MIM:610628]; also known as hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. KAL4 patients have variable degrees of olfactory and reproductive dysfunction, but do not show any of the occasional clinical anomalies reported in Kallmann syndrome such as renal agenesis, cleft lip/palate, selective tooth agenesis, and bimanual synkinesis.
  • 序列相似性Belongs to the AVIT (prokineticin) family.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • BV8 antibody
    • Bv8 homolog antibody
    • MIT1 antibody
    • PK2 antibody
    • PROK2 antibody
    • PROK2_HUMAN antibody
    • Prokineticin-2 antibody
    • Protein Bv8 homolog antibody
    see all

Anti-Prokineticin 2 antibody 图像

  • All lanes : Anti-Prokineticin 2 antibody (ab87360) at 1 µg/ml

    Lane 1 : Human testis tissue lysate - total protein (ab30257)
    Lane 2 : Human small intestine tissue lysate - total protein (ab29276)
    Lane 3 : Testis (Mouse) Tissue Lysate
    Lane 4 : Testis (Rat) Tissue Lysate

    Lysates/proteins at 10 µg per lane.

    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 14 kDa
    Observed band size : 21 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 115 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 20 minutes

Anti-Prokineticin 2 antibody (ab87360)参考文献

ab87360 has not yet been referenced specifically in any publications.

Product Wall

L'anticorps anti-Prokineticin 2 ab87360 a été caractérisé en Western Blot selon le protocole suivant:

Conditions dénaturantes et réductrices
10µg de lysat par puit
Saturation de la m...

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