Anti-Prokineticin 2抗体(ab76747)


  • 产品名称
    Anti-Prokineticin 2抗体
    参阅全部 Prokineticin 2 一抗
  • 描述
    兔多克隆抗体to Prokineticin 2
  • 经测试应用
    适用于: WB, IHC-Fr, IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide derived from the C terminal region of human Prokineticin 2



Our Abpromise guarantee covers the use of ab76747 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/200. Predicted molecular weight: 14 kDa.Can be blocked with Prokineticin 2 peptide (ab140536).
IHC-Fr 1/100 - 1/1000.
IHC-P 1/100 - 1/1000.


  • 功能
    May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.
  • 组织特异性
    Expressed in the testis and, at low levels, in the small intestine.
  • 疾病相关
    Defects in PROK2 are the cause of Kallmann syndrome type 4 (KAL4) [MIM:610628]; also known as hypogonadotropic hypogonadism and anosmia. Anosmia or hyposmia is related to the absence or hypoplasia of the olfactory bulbs and tracts. Hypogonadism is due to deficiency in gonadotropin-releasing hormone and probably results from a failure of embryonic migration of gonadotropin-releasing hormone-synthesizing neurons. KAL4 patients have variable degrees of olfactory and reproductive dysfunction, but do not show any of the occasional clinical anomalies reported in Kallmann syndrome such as renal agenesis, cleft lip/palate, selective tooth agenesis, and bimanual synkinesis.
  • 序列相似性
    Belongs to the AVIT (prokineticin) family.
  • 细胞定位
  • Information by UniProt
  • 数据库链接
  • 别名
    • BV8 antibody
    • Bv8 homolog antibody
    • MIT1 antibody
    • PK2 antibody
    • PROK2 antibody
    • PROK2_HUMAN antibody
    • Prokineticin-2 antibody
    • Protein Bv8 homolog antibody
    see all

Anti-Prokineticin 2 antibody 图像

  • A: ab76747 staining Prokinectin 2 in Mouse testis by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections).
    B: Negative control treated with preimmune serum.
    Both sections counterstained with haematoxylin.

Anti-Prokineticin 2 antibody (ab76747)参考文献

ab76747 has not yet been referenced specifically in any publications.

Product Wall

Yes, the antibody does cross-react with rat PK2, and also mouse.

Yes ab76747 cross reacts with mouse.

Thank you for your response.

As in Point 2 in the previous e-mail describes, the discount code will be for the original value of the product. You can use and test different fixative to chec which one would work better in your experimental sys...

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Thank you very much for your interest our AbTrial program.

To our knowledge, ab76747 has not been tested in murine system. However by participating in our AbTrial program you can now use our products in an untested application or specie...

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Thank you for your inquiry.

I am happy to confirm that we now have added the blocking peptide for this antibody to out catalog.

Please follow this link to the datasheet of the blocking peptide:



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Thank you very much for your interest in ab76747.
To our knowledge, ab76747 has not been tested in radioimmunoassay (RIA) and we predict that mouse and rat tissue. Therefore, I can offer a discount off a future purchase if you buy ab76747 now, tes...

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