Anti-Prokineticin 1抗体(Biotin) (ab84014)

概述

  • 产品名称
    Anti-Prokineticin 1抗体(Biotin)
    参阅全部 Prokineticin 1 一抗
  • 描述
    山羊多克隆抗体to Prokineticin 1 (Biotin)
  • 偶联物
    Biotin
  • 经测试应用
    适用于: ELISA, Sandwich ELISA, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Highly pure (>98%) recombinant human Prokineticin 1.

性能

  • 形式
    Lyophilised:Centrifuge vial prior to opening. Reconstitute in 50 µl of sterile PBS containing 0.1 % BSA to give a concentration of 1.0 mg/ml.
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    ab84014 is sterile filtered. ab84014 was purified by affinity chromatography and then biotinylated.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab84014 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
Sandwich ELISA
WB
  • 应用说明
    ELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant human Prokineticin 1.
    sELISA: Use at a concentration of 0.25 - 1 µg/ml. Allows the detection of at least 0.2 - 0.4 ng/well of recombinant human Prokineticin 1.
    WB: Use at a concentration of 0.1 - 0.2 µg/ml. The detection limit for recombinant human Prokineticin 1 is 1.5 - 3.0 ng/lane, under either reducing or non reducing conditions. Predicted molecular weight: 12 kDa.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能
      Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis.
    • 组织特异性
      Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta.
    • 序列相似性
      Belongs to the AVIT (prokineticin) family.
    • 发展阶段
      In adult testis, is strongly expressed only in Leydig cells. In testicular tumors, expressed specifically in Leydig cell tumors (at protein level). Expressed from 14 weeks until birth in fetal testis.
    • 细胞定位
      Secreted.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Black mamba toxin related protein antibody
      • EG VEGF antibody
      • EG-VEGF antibody
      • EGVEGF antibody
      • Endocrine-gland-derived vascular endothelial growth factor antibody
      • Mambakine antibody
      • PK1 antibody
      • PRK1 antibody
      • PROK1 antibody
      • PROK1_HUMAN antibody
      • Prokineticin-1 antibody
      see all

    实验方案

    文献

    ab84014 has not yet been referenced specifically in any publications.

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